Global burden of transmitted HIV drug resistance and HIV-exposure categories: a systematic review and meta-analysis

QD Pham, DP Wilson, MG Law, AD Kelleher, L Zhang - Aids, 2014 - journals.lww.com
Objectives: Our aim was to review the global disparities of transmitted HIV drug resistance
(TDR) in antiretroviral-naive MSM, people who inject drugs (PWID) and heterosexual …

[HTML][HTML] The role of phylogenetics in discerning HIV-1 mixing among vulnerable populations and geographic regions in sub-Saharan Africa: a systematic review

GM Nduva, J Nazziwa, AS Hassan, EJ Sanders… - Viruses, 2021 - mdpi.com
To reduce global HIV-1 incidence, there is a need to understand and disentangle HIV-1
transmission dynamics and to determine the geographic areas and populations that act as …

[HTML][HTML] HIV-1 virologic failure and acquired drug resistance among first-line antiretroviral experienced adults at a rural HIV clinic in coastal Kenya: a cross-sectional …

AS Hassan, HM Nabwera, SM Mwaringa… - AIDS research and …, 2014 - Springer
Background An increasing number of people on antiretroviral therapy (ART) in sub-Saharan
Africa has led to declines in HIV related morbidity and mortality. However, virologic failure …

HIV-1 second-line failure and drug resistance at high-level and low-level viremia in Western Kenya

R Kantor, A DeLong, L Schreier, M Reitsma, E Kemboi… - Aids, 2018 - journals.lww.com
Objective: Characterize failure and resistance above and below guidelines-recommended
1000 copies/ml virologic threshold, upon second-line failure. Design: Cross-sectional study …

Prevalence of pre-antiretroviral-treatment drug resistance by gender, age, and other factors in HIV-infected individuals initiating therapy in Kenya, 2013–2014

RA Silverman, IA Beck, C Kiptinness… - The Journal of …, 2017 - academic.oup.com
Background Pre-antiretroviral-treatment drug resistance (PDR) is a predictor of human
immunodeficiency virus (HIV) treatment failure. We determined PDR prevalence and …

[HTML][HTML] Surveillance of HIV-1 pol transmitted drug resistance in acutely and recently infected antiretroviral drug-naïve persons in rural western Kenya

H Onywera, D Maman, S Inzaule, E Auma, K Were… - PloS one, 2017 - journals.plos.org
HIV-1 transmitted drug resistance (TDR) is of increasing public health concern in sub-
Saharan Africa with the rollout of antiretroviral (ARV) therapy. Such data are, however …

[HTML][HTML] HIV-1 transmission patterns within and between risk groups in coastal Kenya

GM Nduva, AS Hassan, J Nazziwa, SM Graham… - Scientific reports, 2020 - nature.com
HIV-1 transmission patterns within and between populations at different risk of HIV-1
acquisition in Kenya are not well understood. We investigated HIV-1 transmission networks …

Quantifying rates of HIV-1 flow between risk groups and geographic locations in Kenya: A country-wide phylogenetic study

GM Nduva, F Otieno, J Kimani, E Wahome… - Virus …, 2022 - academic.oup.com
In Kenya, HIV-1 key populations including men having sex with men (MSM), people who
inject drugs (PWID) and female sex workers (FSW) are thought to significantly contribute to …

Oligonucleotide ligation assay detects HIV drug resistance associated with virologic failure among antiretroviral-naive adults in Kenya

MH Chung, IA Beck, S Dross, K Tapia… - JAIDS Journal of …, 2014 - journals.lww.com
Background: Transmitted drug resistance (TDR) is increasing in some areas of Africa.
Detection of TDR may predict virologic failure of first-line nonnucleoside reverse …

[HTML][HTML] HIV-1 subtype diversity, transmission networks and transmitted drug resistance amongst acute and early infected MSM populations from Coastal Kenya

AS Hassan, J Esbjörnsson, E Wahome, A Thiong'o… - PLoS …, 2018 - journals.plos.org
Background HIV-1 molecular epidemiology amongst men who have sex with men (MSM) in
sub-Saharan Africa remains not well characterized. We aimed to determine HIV-1 subtype …