Decreased left heart flow in fetal lambs causes left heart hypoplasia and pro-fibrotic tissue remodeling

MS Reuter, DJ Sokolowski, J Javier Diaz-Mejia… - Communications …, 2023 - nature.com
Low blood flow through the fetal left heart is often conjectured as an etiology for hypoplastic
left heart syndrome (HLHS). To investigate if a decrease in left heart flow results in growth …

C-MORE: A high-content single-cell morphology recognition methodology for liquid biopsies toward personalized cardiovascular medicine

J Furkel, M Knoll, S Din, NV Bogert, T Seeger… - Cell Reports …, 2021 - cell.com
Cellular morphology has the capacity to serve as a surrogate for cellular state and
functionality. However, primary cardiomyocytes, the standard model in cardiovascular …

Deep learning resolves myovascular dynamics in the failing human heart

A Karpurapu, HA Williams, P DeBenedittis… - Basic to Translational …, 2024 - jacc.org
The adult mammalian heart harbors minute levels of cycling cardiomyocytes (CMs). Large
numbers of images are needed to accurately quantify cycling events using microscopy …

Mathematical Modelling for Automatic Cell Contractions Detection and Their Directions in Artificially Grown Human Cardiomyocytes

M Szymkowski, J Goła̧b, K Perz, B Jura - International Conference on …, 2024 - Springer
Mathematical models can be used in diversified problems. They are consumed for precise
simulations (eg, in digital twins) but also can be aligned with slightly different ideas-for …

Mathematical Modelling for Automatic

M Szymkowski, J Gołąb, K Perz2D - … Information Systems and …, 2024 - books.google.com
Mathematical models can be used in diversified problems. They are consumed for precise
simulations (eg, in digital twins) but also can be aligned with slightly different ideas-for …

Cardiovascular applications of artificial intelligence in research, diagnosis, and disease management

V Rajagopalan, H Cao - Biomedical and Business Applications …, 2022 - igi-global.com
Despite significant advancements in diagnosis and disease management, cardiovascular
(CV) disorders remain the No. 1 killer both in the United States and across the world, and …

Automated identification of cardiomyocyte nuclei in H&E-stained heart tissue with CycleGAN

MH Udin, ST Doyle, CN Ionita… - … 2023: Digital and …, 2023 - spiedigitallibrary.org
Purpose: Identification of cardiomyocyte nuclei is of great importance when assessing heart
tissue for cardiovascular disease. However, manual identification of cardiomyocyte nuclei in …