Atualmente, é amplamente aceita a definição da doença renal crônica (DRC) que se baseia
em alterações na taxa de filtração glomerular e/ou presença de lesão parenquimatosa …

Health-related quality of life (QOL) refers to the measure of a patient [apos] s functioning,
well-being, and general health perception in each of three domains: physical, psychological …

Results Of the 145 patients enrolled, 143 were evaluable for efficacy. Overall, 92% of
patients achieved hemoglobin response. Higher compared with lower starting doses led to …

Introduction: Chronic kidney disease as a public health problem. Chronic kidney disease is
a worldwide public health problem. In the United States, there is a rising incidence and …

Background Whether correction of anemia in patients with stage 3 or 4 chronic kidney
disease improves cardiovascular outcomes is not established. Methods We randomly …

Abstract Background Roxadustat (FG-4592) is an oral hypoxia-inducible factor prolyl
hydroxylase inhibitor that stimulates erythropoiesis. This Phase 2a study tested efficacy (Hb …

Renal anemia is a complication of chronic kidney disease. Guidelines for safe and effective
treatment in patients with renal anemia are needed. The Japanese Society for Dialysis …

Background: Previous meta-analyses suggest that treatment with erythropoiesis-stimulating
agents (ESAs) in chronic kidney disease (CKD) increases the risk for death. Additional …

Anemia associated with chronic renal insufficiency (CRI) may have substantial clinical and
public health importance, but little is known about its epidemiology. This study aims to …

BACKGROUND Hemoglobin increases have been associated with quality of life (QOL)
improvements in anemic cancer patients treated with epoetin alfa, but intervention generally …