Uveitis is a sight-threatening disease caused by autoimmune or infection-related immune
responses. Studies in experimental autoimmune uveitis and in human diseases imply that …

Abstract IL-17-producing γδ (γδ17) T cells form a versatile subset of cells that respond
rapidly to innate stimuli and support the pro-inflammatory functions of different myeloid and …

April 25 and 26, 2008, in Fort Lauderdale, Florida. This conference series, funded by the
ARVO Foundation for Eye Research through a grant from Pfizer Ophthalmics, provides an …

The eye and the brain are prototypical tissues manifesting immune privilege (IP) in which
immune responses to foreign antigens, particularly alloantigens are suppressed, and even …

Understanding the role of different subtypes of tumor-infiltrating lymphocytes (TIL) in the
immunosuppressive tumor microenvironment is essential for improving cancer treatment …

Over the last several years, a number of papers have called attention to a distinct population
of γδ T cells preferentially found in the dermis of the skin of normal mice. These cells appear …

Juvenile idiopathic arthritis (JIA) is the most common childhood rheumatic disease and the
most prevalent systemic disorder in children with uveitis. The current prevailing opinion is …

Autoimmune diseases caused by T cells can arise from either T-helper 1 (Th1) or T-helper
17 (Th17)-type pathogenic T cells. However, it is unclear whether these two T-cell subsets …

Th 17 cells have been implicated in the pathogenesis of colitis; however, a cellular
mechanism by which colitogenic Th17 immunity arises in vivo remains unclear. In this study …

We have previously reported that, depending on their activation status, mouse γδ T cells can
either enhance or inhibit the activity of IL-17+ autoreactive T cells in experimental …