Fear generalization and anxiety: behavioral and neural mechanisms
JE Dunsmoor, R Paz - Biological psychiatry, 2015 - Elsevier
Fear can be an adaptive emotion that helps defend against potential danger. Classical
conditioning models elegantly describe how animals learn which stimuli in the environment …
conditioning models elegantly describe how animals learn which stimuli in the environment …
Fear generalization in humans: systematic review and implications for anxiety disorder research
Fear generalization, in which conditioned fear responses generalize or spread to related
stimuli, is a defining feature of anxiety disorders. The behavioral consequences of …
stimuli, is a defining feature of anxiety disorders. The behavioral consequences of …
Laboratory models of post-traumatic stress disorder: The elusive bridge to translation
Post-traumatic stress disorder (PTSD) is a debilitating mental illness composed of a
heterogeneous collection of symptom clusters. The unique nature of PTSD as arising from a …
heterogeneous collection of symptom clusters. The unique nature of PTSD as arising from a …
Ventromedial prefrontal cortex reactivity is altered in generalized anxiety disorder during fear generalization
Background Fear generalization is thought to contribute to the development and
maintenance of anxiety symptoms and accordingly has been the focus of recent research …
maintenance of anxiety symptoms and accordingly has been the focus of recent research …
[HTML][HTML] Pain: a precision signal for reinforcement learning and control
B Seymour - Neuron, 2019 - cell.com
Since noxious stimulation usually leads to the perception of pain, pain has traditionally been
considered sensory nociception. But its variability and sensitivity to a broad array of …
considered sensory nociception. But its variability and sensitivity to a broad array of …
Fear one, fear them all: A systematic review and meta-analysis of fear generalization in pathological anxiety
L Fraunfelter, ABM Gerdes, GW Alpers - Neuroscience & Biobehavioral …, 2022 - Elsevier
It is a defining feature of anxiety disorders that fear is elicited by a circumscribed class of
stimuli rather than by only one specific exemplar of that class. Therefore, fear generalization …
stimuli rather than by only one specific exemplar of that class. Therefore, fear generalization …
[HTML][HTML] The relation between anxious personality traits and fear generalization in healthy subjects: A systematic review and meta-analysis
Background Anxious personality characteristics form a risk factor for anxiety disorders. A
proposed mechanistic pathway is that anxious personality could lead to greater vulnerability …
proposed mechanistic pathway is that anxious personality could lead to greater vulnerability …
Role of conceptual knowledge in learning and retention of conditioned fear
Associating sensory cues with aversive outcomes is a relatively basic process shared across
species. Yet higher-order cognitive processes likely contribute to associative fear learning in …
species. Yet higher-order cognitive processes likely contribute to associative fear learning in …
Maladaptive behavioral consequences of conditioned fear-generalization: a pronounced, yet sparsely studied, feature of anxiety pathology
B van Meurs, N Wiggert, I Wicker, S Lissek - Behaviour research and …, 2014 - Elsevier
Fear-conditioning experiments in the anxiety disorders focus almost exclusively on passive-
emotional, Pavlovian conditioning, rather than active-behavioral, instrumental conditioning …
emotional, Pavlovian conditioning, rather than active-behavioral, instrumental conditioning …
Generalization of human fear acquisition and extinction within a novel arbitrary stimulus category
Adaptive anxiety relies on a balance between the generalization of fear acquisition and fear
extinction. Research on fear (extinction) generalization has focused mostly on perceptual …
extinction. Research on fear (extinction) generalization has focused mostly on perceptual …