Inflammatory bowel diseases (IBD) arise from a convergence of genetic risk, environmental
factors, and gut microbiota, where each is necessary but not sufficient to cause disease …

The monoamine serotonin, 5-hydroxytryptamine (5-HT), is a remarkable molecule with
conserved production in prokaryotes and eukaryotes and a wide range of functions. In the …

Leukocyte trafficking to the gastrointestinal tract is recognized to play a role in the
pathogenesis of inflammatory bowel disease (IBD). Integrins are expressed on immune cells …

Nowadays, non-biological treatments remain valuable approaches among the therapeutic
armamentarium of inflammatory bowel disease (IBD). Mesalamine is the core treatment of …

Inflammation often develops from acute, chronic, or auto-inflammatory disorders that can
lead to compromised organ function. Cannabis (Cannabis sativa) has been used to treat …

When reactive oxygen species (ROS) accumulate in the body, they can lead to inflammatory
bowel disease (IBD) through their oxidative damages to DNA, proteins, and lipids. In this …

Background Recent evidence is supporting the notion of a microbiological and
immunological continuum on the gum–gut axis in health and disease. Therefore, the …

Butyrate is a short-chain fatty acid that plays a key role in maintaining gut homeostasis as
well as the integrity of the intestinal barrier. In the present study, we investigated the effect of …

The burden of inflammatory bowel diseases (IBD), including Crohn's disease (CD) and
ulcerative colitis (UC), is increasing worldwide. The aim of the present study was to …

Background The inflammatory bowel diseases, Crohn's disease and ulcerative colitis are
related multifactorial diseases. Their pathogenesis is influenced by each individual's …