A literature review of traumatic brain injury biomarkers
Research into TBI biomarkers has accelerated rapidly in the past decade owing to the
heterogeneous nature of TBI pathologies and management, which pose challenges to TBI …
heterogeneous nature of TBI pathologies and management, which pose challenges to TBI …
Traumatic brain injury: classification, models, and markers
D Najem, K Rennie… - … and cell biology, 2018 - cdnsciencepub.com
Traumatic brain injury (TBI) is a leading cause of morbidity and mortality worldwide. Due to
its high incidence rate and often long-term sequelae, TBI contributes significantly to …
its high incidence rate and often long-term sequelae, TBI contributes significantly to …
Early predictors of outcome after mild traumatic brain injury (UPFRONT): an observational cohort study
J van der Naalt, ME Timmerman, ME de Koning… - The Lancet …, 2017 - thelancet.com
Background Mild traumatic brain injury (mTBI) accounts for most cases of TBI, and many
patients show incomplete long-term functional recovery. We aimed to create a prognostic …
patients show incomplete long-term functional recovery. We aimed to create a prognostic …
Concussion as a multi-scale complex system: an interdisciplinary synthesis of current knowledge
Traumatic brain injury (TBI) has been called “the most complicated disease of the most
complex organ of the body” and is an increasingly high-profile public health issue. Many …
complex organ of the body” and is an increasingly high-profile public health issue. Many …
Assessing neuronal and astrocyte derived exosomes from individuals with mild traumatic brain injury for markers of neurodegeneration and cytotoxic activity
CN Winston, HK Romero, M Ellisman… - Frontiers in …, 2019 - frontiersin.org
Mild traumatic brain injury (mTBI) disproportionately affects military service members and is
very difficult to diagnose. To-date, there is currently no blood-based, diagnostic biomarker …
very difficult to diagnose. To-date, there is currently no blood-based, diagnostic biomarker …
Multiparametric MRI changes persist beyond recovery in concussed adolescent hockey players
Objective: To determine whether multiparametric MRI data can provide insight into the acute
and long-lasting neuronal sequelae after a concussion in adolescent athletes. Methods …
and long-lasting neuronal sequelae after a concussion in adolescent athletes. Methods …
[HTML][HTML] Optic tract injury after closed head traumatic brain injury in mice: A model of indirect traumatic optic neuropathy
NK Evanson, F Guilhaume-Correa, JP Herman… - PLoS …, 2018 - journals.plos.org
Adult male C57BL/6J mice have previously been reported to have motor and memory
deficits after experimental closed head traumatic brain injury (TBI), without associated gross …
deficits after experimental closed head traumatic brain injury (TBI), without associated gross …
Mild, moderate and severe: terminology implications for clinical and experimental traumatic brain injury
S Yamamoto, HS Levin, DS Prough - Current opinion in …, 2018 - journals.lww.com
Many patients after mild or moderate TBI suffer long-term sequelae and should be
considered a major target for translational research. Treatments that improve outcome in …
considered a major target for translational research. Treatments that improve outcome in …
The evolving role of extracellular vesicles (exosomes) as biomarkers in traumatic brain injury: Clinical perspectives and therapeutic implications
Developing effective disease-modifying therapies for neurodegenerative diseases (NDs)
requires reliable diagnostic, disease activity, and progression indicators. While desirable …
requires reliable diagnostic, disease activity, and progression indicators. While desirable …
[HTML][HTML] Scared or scarred: Could 'dissociogenic'lesions predispose to nonepileptic seizures after head trauma?
A history of head injury is common in patients with psychogenic nonepileptic seizures
(PNES). This association has so far been interpreted as either spurious or psychologically …
(PNES). This association has so far been interpreted as either spurious or psychologically …