[HTML][HTML] The relative effectiveness of five antiepileptic drugs in treatment of benzodiazepine-resistant convulsive status epilepticus: a meta-analysis of published …

Z Yasiry, SD Shorvon - Seizure, 2014 - Elsevier
Purpose Systematic evaluation of published evidence-base of the efficacy of five
antiepileptic drugs–lacosamide, levetiracetam, valproate, phenytoin and phenobarbital–in …

Evidence-based guideline: treatment of convulsive status epilepticus in children and adults: report of the Guideline Committee of the American Epilepsy Society

T Glauser, S Shinnar, D Gloss, B Alldredge… - Epilepsy …, 2016 - journals.sagepub.com
CONTEXT: The optimal pharmacologic treatment for early convulsive status epilepticus is
unclear. OBJECTIVE: To analyze efficacy, tolerability and safety data for anticonvulsant …

Clinical pharmacology and pharmacokinetics of levetiracetam

C Wright, J Downing, D Mungall, O Khan… - Frontiers in …, 2013 - frontiersin.org
Status epilepticus and acute repetitive seizures still pose a management challenge despite
the recent advances in the field of epilepsy. Parenteral formulations of old anticonvulsants …

Management of generalised convulsive status epilepticus (SE): A prospective randomised controlled study of combined treatment with intravenous lorazepam with …

RC Mundlamuri, S Sinha, DK Subbakrishna… - Epilepsy research, 2015 - Elsevier
Objective This study was conducted to compare the efficacy of phenytoin, valproate and
levetiracetam in patients with GCSE. Methods This randomised controlled prospective study …

[HTML][HTML] Formation strategies, mechanism of intracellular delivery and potential clinical applications of pH-sensitive liposomes

X Liu, G Huang - Asian journal of pharmaceutical sciences, 2013 - Elsevier
Abstract pH-sensitive liposomes are designed to specifically triggered release the loaded
drugs in response to the change of pH in the surrounding serum. So pH-sensitive liposomes …

[HTML][HTML] Clinical efficacy and safety of injectable levetiracetam versus phenytoin as second-line therapy in the management of generalized convulsive status …

N Noureen, S Khan, A Khursheed… - Journal of clinical …, 2019 - synapse.koreamed.org
Background and Purpose There is sparsity of quality evidence for the use of drugs after first-
line benzodiazepines in convulsive status epilepticus in children. The aim of the study was …

Status epilepticus—work-Up and management in children

CB Aguilar, IS Fernández… - Seminars in …, 2020 - thieme-connect.com
Status epilepticus (SE) is one of the most common neurological emergencies in children and
has a mortality of 2 to 4%. Admissions for SE are very resource-consuming, especially in …

Epilepsy emergencies: diagnosis and management

B Foreman, LJ Hirsch - Neurologic clinics, 2012 - neurologic.theclinics.com
Emergencies in epilepsy may be encountered in the home, en route to a nearby hospital, in
the emergency department (ED), in the hospital, or in an intensive care unit (ICU). Adequate …

[HTML][HTML] Levetiracetam as alternative stage two antiepileptic drug in status epilepticus: a systematic review

J Zelano, E Kumlien - Seizure, 2012 - Elsevier
BACKGROUND: The role of new antiepileptic drugs (AED) in the treatment of status
epilepticus (SE) is of interest, especially in benzodiazepine-resistant status epilepticus …

Treatment of status epilepticus after traumatic brain injury using an antiseizure drug combined with a tissue recovery enhancer revealed by systems biology

N Kajevu, A Lipponen, P Andrade, I Bañuelos… - International Journal of …, 2023 - mdpi.com
We tested a hypothesis that in silico-discovered compounds targeting traumatic brain injury
(TBI)-induced transcriptomics dysregulations will mitigate TBI-induced molecular pathology …