In this review, we summarize the origin and advancements of iridium-catalyzed asymmetric
allylic substitution reactions during the past two decades. Since the first report in 1997, Ir …

Conspectus The catalytic, asymmetric synthesis of complex molecules has been a core
focus of our research program for some time because developments in the area can have an …

Alcohols are abundant and attractive feedstock molecules for organic synthesis. Many
methods for their functionalization require them to first be converted into a more activated …

A catalytic, enantio‐, and diastereoselective formation of sulfenyl acetals bearing multiple
stereogenic centers is reported. Alkenyl aldehydes undergo a chiral thiiranium ion initiated …

Ketones and aldehydes are employed as enol O-nucleophiles in an iridium-catalyzed
asymmetric allylic substitution reaction. The reaction proceeds well in the presence of a well …

Trimethyl orthoacetate and ethylene glycol mono‐vinyl ether are employed in iridium‐
catalyzed enantioselective allylation reactions. The method documented enables their …

Straightforward access to a series of the cytotoxic sphingolipid-derived alkaloids possessing
a pyrrolidine unit and a long hydrophobic side chain was accomplished. Two simple …

Asymmetric allylation represents an important reaction applied in the natural product
synthesis. The stereoselective introduction of an allyl group allows to obtain versatile chiral …

The copper-catalysed azide-alkyne cycloaddition was applied to prepare three enantiomeric
pairs of heterodimers containing a tacrine residue and a 1, 4-dideoxy-1, 4-imino-d-arabinitol …

The iminosugar core of natural glyphaeaside C, originally assigned as a derivative of the
piperidine natural product 1-deoxynojirimycin (DNJ), has been revised as a derivative of 2, 5 …