Role of leptin in the activation of immune cells

P Fernández-Riejos, S Najib… - Mediators of …, 2010 - Wiley Online Library
Adipose tissue is an active endocrine organ that secretes various humoral factors
(adipokines), and its shift to production of proinflammatory cytokines in obesity likely …

Biomarkers of inflammation and the etiology of sepsis

I Grondman, A Pirvu, A Riza, M Ioana… - Biochemical Society …, 2020 - portlandpress.com
Sepsis is characterized as a life-threatening organ dysfunction syndrome that is caused by a
dysregulated host response to infection. The main etiological causes of sepsis are bacterial …

Effect of obesity on intensive care morbidity and mortality: a meta-analysis

ME Akinnusi, LA Pineda, AA El Solh - Critical care medicine, 2008 - journals.lww.com
Objective: To evaluate the effect of obesity on intensive care unit mortality, duration of
mechanical ventilation, and intensive care unit length of stay among critically ill medical and …

Obesity, adipokines and neuroinflammation

A Aguilar-Valles, W Inoue, C Rummel, GN Luheshi - Neuropharmacology, 2015 - Elsevier
Global levels of obesity are reaching epidemic proportions, leading to a dramatic increase in
incidence of secondary diseases and the significant economic burden associated with their …

Role of leptin as a link between metabolism and the immune system

A Pérez-Pérez, T Vilariño-García… - Cytokine & growth factor …, 2017 - Elsevier
Leptin is an adipocyte-derived hormone not only with an important role in the central control
of energy metabolism, but also with many pleiotropic effects in different physiological …

Anorexia nervosa and the immune system—a narrative review

D Gibson, PS Mehler - Journal of clinical medicine, 2019 - mdpi.com
The pathogenesis of an increasing number of chronic diseases is being attributed to effects
of the immune system. However, its role in the development and maintenance of anorexia …

Leptin functions in infectious diseases

R Maurya, P Bhattacharya, R Dey… - Frontiers in …, 2018 - frontiersin.org
Leptin, a pleiotropic protein has long been recognized to play an important role in the
regulation of energy homeostasis, metabolism, neuroendocrine function, and other …

Role of adipose tissue as an inflammatory organ in human diseases

A Schaffler, U Muller-Ladner, J Scholmerich… - Endocrine …, 2006 - academic.oup.com
Reviews on the inflammatory role of adipose tissue outside the field of metabolism are rare.
There is increasing evidence provided by numerous basic research studies from nearly all …

Leptin indirectly activates human neutrophils via induction of TNF-α

H Zarkesh-Esfahani, AG Pockley, Z Wu… - The Journal of …, 2004 - journals.aai.org
Leptin, the satiety hormone, appears to act as a link between nutritional status and immune
function. It has been shown to elicit a number of immunoregulatory effects, including the …

Underlying host risk factors for nontuberculous mycobacterial lung disease

ED Chan, MD Iseman - Seminars in respiratory and critical care …, 2013 - thieme-connect.com
Nontuberculous mycobacteria (NTM) are environmental microbes that cause a variety of
human diseases, particularly chronic lung infections. Despite the fact that NTM are …