The nephropathy of sickle cell trait and sickle cell disease

KI Ataga, SL Saraf, VK Derebail - Nature Reviews Nephrology, 2022 - nature.com
Sickle cell syndromes, including sickle cell disease (SCD) and sickle cell trait, are
associated with multiple kidney abnormalities. Young patients with SCD have elevated …

Inequities in kidney health and kidney care

R Vanholder, L Annemans, M Braks… - Nature Reviews …, 2023 - nature.com
Health inequity refers to the existence of unnecessary and unfair differences in the ability of
an individual or community to achieve optimal health and access appropriate care. Kidney …

[HTML][HTML] Large language models encode clinical knowledge

K Singhal, S Azizi, T Tu, SS Mahdavi, J Wei, HW Chung… - Nature, 2023 - nature.com
Large language models (LLMs) have demonstrated impressive capabilities, but the bar for
clinical applications is high. Attempts to assess the clinical knowledge of models typically …

Large language models encode clinical knowledge

K Singhal, S Azizi, T Tu, SS Mahdavi, J Wei… - arXiv preprint arXiv …, 2022 - arxiv.org
Large language models (LLMs) have demonstrated impressive capabilities in natural
language understanding and generation, but the quality bar for medical and clinical …

A toolbox for surfacing health equity harms and biases in large language models

SR Pfohl, H Cole-Lewis, R Sayres, D Neal, M Asiedu… - Nature Medicine, 2024 - nature.com
Large language models (LLMs) hold promise to serve complex health information needs but
also have the potential to introduce harm and exacerbate health disparities. Reliably …

Performance of creatinine-based equations to estimate glomerular filtration rate in White and Black populations in Europe, Brazil and Africa

P Delanaye, E Vidal-Petiot, J Björk… - Nephrology Dialysis …, 2023 - academic.oup.com
ABSTRACT Background A new Chronic Kidney Disease Epidemiology Collaboration
equation without the race variable has been recently proposed (CKD-EPIAS). This equation …

The new, race-free, Chronic Kidney Disease Epidemiology Consortium (CKD-EPI) equation to estimate glomerular filtration rate: is it applicable in Europe? A position …

P Delanaye, E Schaeffner, M Cozzolino… - Clinical Chemistry and …, 2023 - degruyter.com
The EFLM recommends not to implement the race-free Chronic Kidney Disease
Epidemiology Consortium (CKD-EPI) equation in European laboratories and to keep the …

Chronic kidney disease and the global public health agenda: an international consensus

A Francis, MN Harhay, A Ong… - Nature Reviews …, 2024 - nature.com
Early detection is a key strategy to prevent kidney disease, its progression and related
complications, but numerous studies show that awareness of kidney disease at the …

[HTML][HTML] Investigating for bias in healthcare algorithms: a sex-stratified analysis of supervised machine learning models in liver disease prediction

I Straw, H Wu - BMJ health & care informatics, 2022 - ncbi.nlm.nih.gov
Objectives The Indian Liver Patient Dataset (ILPD) is used extensively to create algorithms
that predict liver disease. Given the existing research describing demographic inequities in …

Artificial intelligence-enabled decision support in nephrology

TJ Loftus, B Shickel, T Ozrazgat-Baslanti… - Nature Reviews …, 2022 - nature.com
Kidney pathophysiology is often complex, nonlinear and heterogeneous, which limits the
utility of hypothetical-deductive reasoning and linear, statistical approaches to diagnosis and …