Inflammatory and microbiota-related regulation of the intestinal epithelial barrier

G Barbara, MR Barbaro, D Fuschi, M Palombo… - Frontiers in …, 2021 - frontiersin.org
The intestinal epithelial barrier (IEB) is one of the largest interfaces between the
environment and the internal milieu of the body. It is essential to limit the passage of harmful …

Epidemiology and pathogenesis of ulcerative colitis

L Du, C Ha - Gastroenterology Clinics, 2020 - gastro.theclinics.com
Ulcerative colitis (UC) is a chronic immune-mediated inflammatory disorder of the colon
(IBD) that is hypothesized to be related to exposure to environmental risk factors leading to …

A comprehensive review and update on ulcerative colitis

M Gajendran, P Loganathan, G Jimenez, AP Catinella… - Disease-a-month, 2019 - Elsevier
Ulcerative colitis (UC) is a chronic idiopathic inflammatory bowel disorder of the colon that
causes continuous mucosal inflammation extending from the rectum to the more proximal …

[PDF][PDF] Third European evidence-based consensus on diagnosis and management of ulcerative colitis. Part 1: definitions, diagnosis, extra-intestinal manifestations …

F Magro, P Gionchetti, R Eliakim… - Journal of Crohn's …, 2017 - academic.oup.com
1.2. Definitions Ulcerative colitis [UC] is a chronic inflammatory condition that causes
continuous mucosal inflammation of the colon, usually without granulomas on biopsy. It …

Association of obesity with risk of early-onset colorectal cancer among women

PH Liu, K Wu, K Ng, AG Zauber, LH Nguyen… - JAMA …, 2019 - jamanetwork.com
Importance Colorectal cancer (CRC) incidence and mortality among individuals younger
than 50 years (early-onset CRC) are increasing. The reasons for such increases are largely …

Crohn disease: epidemiology, diagnosis, and management

JD Feuerstein, AS Cheifetz - Mayo Clinic Proceedings, 2017 - Elsevier
Crohn disease is a chronic idiopathic inflammatory bowel disease condition characterized
by skip lesions and transmural inflammation that can affect the entire gastrointestinal tract …

Epidemiology and risk factors for IBD

AN Ananthakrishnan - Nature reviews Gastroenterology & hepatology, 2015 - nature.com
IBD, comprising Crohn's disease and ulcerative colitis, is a chronic immunologically
mediated disease at the intersection of complex interactions between genetics, environment …

A prospective study of long-term intake of dietary fiber and risk of Crohn's disease and ulcerative colitis

AN Ananthakrishnan, H Khalili, GG Konijeti… - Gastroenterology, 2013 - Elsevier
Background & Aims Increased intake of dietary fiber has been proposed to reduce the risk of
inflammatory bowel disease (Crohn's disease [CD] and ulcerative colitis [UC]). However, few …

Long-term intake of dietary fat and risk of ulcerative colitis and Crohn's disease

AN Ananthakrishnan, H Khalili, GG Konijeti… - Gut, 2014 - gut.bmj.com
Introduction Dietary fats influence intestinal inflammation and regulate mucosal immunity.
Data on the association between dietary fat and risk of Crohn's disease (CD) and ulcerative …

East–West gradient in the incidence of inflammatory bowel disease in Europe: the ECCO-EpiCom inception cohort

J Burisch, N Pedersen, S Čuković-Čavka, M Brinar… - Gut, 2014 - gut.bmj.com
Objective The incidence of inflammatory bowel disease (IBD) is increasing in Eastern
Europe. The reasons for these changes remain unknown. The aim of this study was to …