It has been widely known that oxidative stress disrupts the balance between reactive oxygen
species (ROS) and the antioxidant system in the body. During pregnancy, the physiological …

Byproducts of normal mitochondrial metabolism and homeostasis include the buildup of
potentially damaging levels of reactive oxygen species (ROS), Ca2+, etc., which must be …

Dichlorodihydrofluorescein diacetate (DCFH-DA) has been widely used in detection of
reactive oxygen species (ROS). Unfortunately, the detection process is easily affected by …

An appropriate balance between self-renewal and differentiation is crucial for stem cell
function during both early development and tissue homeostasis throughout life. Recent …

The presence of ROS is a constant feature in living cells metabolizing O2. ROS
concentration and compartmentation determine their physiological or pathological effects …

The pathophysiological mechanism underlying pregnancy complications such as congenital
malformations, miscarriage, preeclampsia, or fetal growth restriction is not entirely known …

The average lifespan of circulating erythrocytes usually exceeds hundred days. Prior to that,
however, erythrocytes may be exposed to oxidative stress in the circulation which could …

Reactive oxygen species (ROS) are highly reactive molecules that arise from a number of
cellular sources, including oxidative metabolism in mitochondria. At low levels they can be …

The resident prokaryotic microbiota of the metazoan gut elicits profound effects on the
growth and development of the intestine. However, the molecular mechanisms of symbiotic …

Cardiomyocytes from human pluripotent stem cells (hPSC-CMs) are increasingly used to
model cardiac disease, test drug efficacy and for safety pharmacology. Nevertheless, a …