Schizophrenia as the price that Homo sapiens pays for language: a resolution of the central paradox in the origin of the species
TJ Crow - Brain research reviews, 2000 - Elsevier
The central paradox of schizophrenia is that the condition, apparently genetic in origin,
persists in spite of a substantial fecundity disadvantage. The hypothesis is proposed that the …
persists in spite of a substantial fecundity disadvantage. The hypothesis is proposed that the …
Y chromosome microdeletions and alterations of spermatogenesis
Three different spermatogenesis loci have been mapped on the Y chromosome and named
“azoospermia factors”(AZFa, b, and c). Deletions in these regions remove one or more of the …
“azoospermia factors”(AZFa, b, and c). Deletions in these regions remove one or more of the …
Functional coherence of the human Y chromosome
BT Lahn, DC Page - Science, 1997 - science.org
A systematic search of the nonrecombining region of the human Y chromosome (NRY)
identified 12 novel genes or families, 10 with full-length complementary DNA sequences. All …
identified 12 novel genes or families, 10 with full-length complementary DNA sequences. All …
[HTML][HTML] Microdeletions in the Y chromosome of infertile men
JL Pryor, M Kent-First, A Muallem… - … England Journal of …, 1997 - Mass Medical Soc
Background Some infertile men with azoospermia or severe oligospermia have small
deletions in regions of the Y chromosome. However, the frequency of such microdeletions …
deletions in regions of the Y chromosome. However, the frequency of such microdeletions …
Defining regions of the Y‐chromosome responsible for male infertility and identification of a fourth AZF region (AZFd) by Y‐chromosome microdeletion detection
M Kent‐First, A Muallem, J Shultz… - Molecular …, 1999 - Wiley Online Library
Cytogenetic and molecular deletion analyses of azoospermic and oligozoospermic males
have suggested the existence of AZoospermia Factor (s)(AZF) residing in deletion intervals …
have suggested the existence of AZoospermia Factor (s)(AZF) residing in deletion intervals …
The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned
R Saxena, LG Brown, T Hawkins, RK Alagappan… - Nature …, 1996 - nature.com
It is widely believed that most or all Y–chromosomal genes were once shared with the X
chromosome. The DAZ gene is a candidate for the human Y–chromosomal Azoospermia …
chromosome. The DAZ gene is a candidate for the human Y–chromosomal Azoospermia …
The ʻbig bangʼ theory of the origin of psychosis and the faculty of language
TJ Crow - Schizophrenia research, 2008 - Elsevier
OBJECTIVE: To achieve a unified concept of the aetiology of psychosis. BACKGROUND:
The nuclear symptoms of “schizophrenia” occur with approximately the same age-and sex …
The nuclear symptoms of “schizophrenia” occur with approximately the same age-and sex …
Paternal, maternal, and biparental molecular markers provide unique windows onto the evolutionary history of macaque monkeys
AJ Tosi, JC Morales, DJ Melnick - Evolution, 2003 - academic.oup.com
We report the results of one of the first intrageneric analyses to simultaneously survey
mitochondrial, Y‐chromosomal, and autosomal loci from the same individuals representing …
mitochondrial, Y‐chromosomal, and autosomal loci from the same individuals representing …
High frequency of well-defined Y-chromosome deletions in idiopathic Sertoli cell-only syndrome
Idiopathic Sertoli cell-only syndrome (SCOS) Is characterized by azoospermia, small testes,
absence of germ cells In the testes, elevated Mick stimulating hormone and normal …
absence of germ cells In the testes, elevated Mick stimulating hormone and normal …
Comparison of Y chromosome and mtDNA phylogenies leads to unique inferences of macaque evolutionary history
AJ Tosi, JC Morales, DJ Melnick - Molecular phylogenetics and evolution, 2000 - Elsevier
We report here the results of one of the first analyses to use male-specific nuclear markers in
elucidating primate phylogenetic relationships at the intrageneric level. Two closely linked Y …
elucidating primate phylogenetic relationships at the intrageneric level. Two closely linked Y …