Molecular docking is a computational technique that predicts the binding affinity of ligands to
receptor proteins. Although it has potential uses in nutraceutical research, it has developed …

Sickle cell disease (SCD) is the most common hereditary hemoglobinopathy. The underlying
pathophysiology of the red blood cell (RBC) leads to pan-systemic complications which …

Sickle cell disease (SCD) is an inherited hemoglobinopathy characterized by chronic
anemia, intravascular hemolysis, and the occurrence of vaso-occlusive crises due to the …

The importance of protecting brain function for people with sickle cell disease (SCD) cannot
be overstated. SCD is associated with multiple cerebrovascular complications that threaten …

Sickle cell disease (SCD) is a common, severe genetic blood disorder. Current
pharmacotherapies are partially effective and allogeneic hematopoietic stem cell …

Abstract Sickle Cell Disease (SCD) is one of the most inherited hematologic diseases
affecting humans. Clinically, there is a progressive multiorgan failure and increased mortality …

Data to guide evidence-based management of pregnant people with sickle cell disease
(SCD) are limited. This international Delphi panel aimed to identify consensus among …

Pyruvate kinase (PK) is a key enzyme in glycolysis, the sole source of adenosine
triphosphate, which is essential for all energy-dependent activities of red blood cells …

Sickle cell disease (SCD) was first described in 1910 in African Americans, and the mutant
hemoglobin S (HbS) was identified by electrophoresis in 1948. Sickle cell disease is the first …

Abstract Background and Objective Gene therapies for sickle cell disease (SCD) may offer
meaningful benefits for patients and society. This study evaluated the cost-effectiveness of …