Imaging-guided targeted radionuclide tumor therapy: From concept to clinical translation

J Sun, Z Huangfu, J Yang, G Wang, K Hu, M Gao… - Advanced Drug Delivery …, 2022 - Elsevier
Since the first introduction of sodium iodide I-131 for use with thyroid patients almost 80
years ago, more than 50 radiopharmaceuticals have reached the markets for a wide range …

Molecular imaging theranostics of neuroendocrine tumors

E Fortunati, N Bonazzi, L Zanoni, S Fanti… - Seminars in Nuclear …, 2023 - Elsevier
Neuroendocrine neoplasms (NEN) are rare and heterogeneous tumors, originating mostly
from the gastro-entero-pancreatic (GEP) tract followed by the lungs. Multidisciplinary …

Clinical translational evaluation of Al18F-NOTA-FAPI for fibroblast activation protein-targeted tumour imaging

S Wang, X Zhou, X Xu, J Ding, S Liu, X Hou… - European journal of …, 2021 - Springer
Purpose In this study, a novel aluminium-[18 F] fluoride (Al 18 F)-labelled 1, 4, 7‑
triazacyclononane-N, N′, N ″-triacetic acid (NOTA)-conjugated fibroblast activation protein …

High in-vivo stability in preclinical and first-in-human experiments with [18F]AlF-RESCA-MIRC213: a 18F-labeled nanobody as PET radiotracer for diagnosis of …

X Qin, X Guo, T Liu, L Li, N Zhou, X Ma, X Meng… - European Journal of …, 2023 - Springer
Abstract Purpose [18F] AlF-RESCA was introduced as a core particularly useful for 18F-
labeling of heat-sensitive biomolecules. However, no translational studies have been …

Comparison of renal clearance of [18F]AlF-RESCA-HER2-BCH and [18F]AlF-NOTA-HER2-BCH in mice and breast cancer patients

J Liu, X Guo, L Wen, L Wang, F Liu, G Song… - European Journal of …, 2023 - Springer
Purpose A novel HER2 affibody-based molecular probe,[18F] AlF-RESCA-HER2-BCH, was
developed for reducing renal uptake, evaluated, and compared with [18F] AlF-NOTA-HER2 …

Targeted cancer therapy: what's new in the field of neuroendocrine neoplasms?

A La Salvia, P Espinosa-Olarte, MDC Riesco-Martinez… - Cancers, 2021 - mdpi.com
Simple Summary Neuroendocrine neoplasms are highly heterogeneous tumors in terms of
primary origin, molecular landscape, clinical presentation and behavior. To date, several …

Current status and future perspective of radiopharmaceuticals in China

J Hu, H Li, Y Sui, J Du - European Journal of Nuclear Medicine and …, 2022 - Springer
Radiopharmaceuticals are essential components of nuclear medicine and serve as one of
the cornerstones of molecular imaging and precision medicine. They provide new means …

Peptides for diagnosis and treatment of ovarian cancer

L Guo, J Wang, N Li, J Cui, Y Su - Frontiers in oncology, 2023 - frontiersin.org
Ovarian cancer is the most deadly gynecologic malignancy, and its incidence is gradually
increasing. Despite improvements after treatment, the results are unsatisfactory and survival …

Advances in the diagnosis and therapeutic management of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs)

K Kaliszewski, M Ludwig, M Greniuk, A Mikuła… - Cancers, 2022 - mdpi.com
Simple Summary Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are a
group of tumors with different clinical manifestations, various localizations in the human …

Recent advances in neuropeptide-related omics and gene editing: Spotlight on NPY and somatostatin and their roles in growth and food intake of fish

X Yu, H Yan, W Li - Frontiers in Endocrinology, 2022 - frontiersin.org
Feeding and growth are two closely related and important physiological processes in living
organisms. Studies in mammals have provided us with a series of characterizations of …