[HTML][HTML] A pragmatic guide to enrichment strategies for mass spectrometry–based glycoproteomics
Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …
implications in molecular biology. This heterogeneity precludes enrichment strategies that …
Therapeutic Fc‐fusion proteins: current analytical strategies
BL Duivelshof, A Murisier, J Camperi… - Journal of separation …, 2021 - Wiley Online Library
Fc‐Fusion proteins represent a successful class of biopharmaceutical products, with already
13 drugs approved in the European Union and United States as well as three biosimilar …
13 drugs approved in the European Union and United States as well as three biosimilar …
Cucurbit [7] uril macrocyclic sensors for optical fingerprinting: predicting protein structural changes to identifying disease-specific amyloid assemblies
In a three-dimensional (3D) representation, each protein molecule displays a specific
pattern of chemical and topological features, which are altered during its misfolding and …
pattern of chemical and topological features, which are altered during its misfolding and …
Host–guest complexation of amphiphilic molecules at the air–water interface prevents oxidation by hydroxyl radicals and singlet oxygen
WC Geng, D Zhang, C Gong, Z Li… - Angewandte Chemie …, 2020 - Wiley Online Library
The oxidation of antioxidants by oxidizers imposes great challenges to both living organisms
and the food industry. Here we show that the host–guest complexation of the carefully …
and the food industry. Here we show that the host–guest complexation of the carefully …
Dynamic host–guest interaction enables autonomous single molecule blinking and super-resolution imaging
Synthetic host–guest complexes are inherently dynamic as they employ weak and reversible
noncovalent interactions for their recognition processes. We strategically exploited dynamic …
noncovalent interactions for their recognition processes. We strategically exploited dynamic …
In-depth characterization of non-human sialic acid (Neu5Gc) in human serum using label-free ZIC-HILIC/MRM-MS
Abstract Sialic acid Neu5Gc, a non-human glycan, is recognized as a new harmful
substance that can cause vascular disease and cancer. Humans are unable to synthesize …
substance that can cause vascular disease and cancer. Humans are unable to synthesize …
Noncovalent Tagging for Identifying Unknown Contaminants of Specific Bioactivity in Environmental Water
H Wen, M Shen, Z Lai, X Peng, YX Ye, J Xu… - Analytical …, 2023 - ACS Publications
Identifying contaminants of specific bioactivities from complicated environmental matrices
remains costly and time-consuming, as it requires us to not only resolve their structures but …
remains costly and time-consuming, as it requires us to not only resolve their structures but …
Barriers for extrusion of a guest from the interior binding cavity of a host: Gas phase experimental and computational results for ion-capped decamethylcucurbit [5] uril …
Factors affecting the extrusion of guests from metal ion-capped decamethylcucurbit [5] uril
(mc5) molecular container complexes are investigated using both collision-induced …
(mc5) molecular container complexes are investigated using both collision-induced …
Application of sample displacement batch chromatography for fractionation of proteoforms
SN Hidayah, A Biabani, M Gaikwad, P Nissen… - …, 2024 - Wiley Online Library
Fractionation of proteoforms is currently the most challenging topic in the field of proteoform
analysis. The need for considering the existence of proteoforms in experimental approaches …
analysis. The need for considering the existence of proteoforms in experimental approaches …
Noncovalently tagged gas phase complex ions for screening unknown contaminant metabolites in plants
M Shen, X Gong, S Huang, Y Shen, YX Ye… - Analytical …, 2021 - ACS Publications
Screening the metabolites of emerging organic contaminants (EOCs) from complicated
biological matrices is an important but challenging task. Although stable isotope labeling …
biological matrices is an important but challenging task. Although stable isotope labeling …