Over centuries, several advances have been made in osteochondral (OC) tissue
engineering to regenerate more biomimetic tissue. As an essential component of tissue …

Objective: Hydrogel scaffolds have attracted attention to develop cellular therapy and tissue
engineering platforms for regenerative medicine applications. Among factors, local …

Materials science has been informed by nonclassical pathways to crystallization, based on
biological processes, about the fabrication of damage-tolerant composite materials. Various …

To assist in bone defect repair, ideal bone regeneration scaffolds should exhibit good
osteoconductivity and osteoinductivity, but for load-bearing applications, they should also …

With the aging population, there is a growing need for mineralized tissue restoration and
synthetic bone substitutes. Previous studies have shown that a polymer-induced liquid …

Despite tremendous attention is given to the construction of biomimetic cementum for
regeneration of tooth cementum, the lack of recapitulating the composition and hierarchical …

Lamellar bone, compactly and ingeniously organized in the hierarchical pattern with 6
ordered scales, is the structural motif of mature bone. Each hierarchical scale exerts an …

The mechanisms underlying the formation of nanocrystalline apatite in vertebrate hard
tissues (ie bones and teeth) remain nebulous. The long-held view of biomineralization via …

Biomineralization processes are responsible for complex and intriguing natural structures,
where organisms regulate the synthesis of organic-inorganic composites with hierarchical …

[en] Polymer-Induced Liquid-Precursor (PILP) mineralization concept is based on ions
stabilization and subsequent amorphous phase mineral formation by high negative …