Immune targets for therapeutic development in depression: towards precision medicine
Over the past two decades, compelling evidence has emerged indicating that immune
mechanisms can contribute to the pathogenesis of major depressive disorder (MDD) and …
mechanisms can contribute to the pathogenesis of major depressive disorder (MDD) and …
Late-life depression: Epidemiology, phenotype, pathogenesis and treatment before and during the COVID-19 pandemic
Y Zhao, X Wu, M Tang, L Shi, S Gong, X Mei… - Frontiers in …, 2023 - frontiersin.org
Late-life depression (LLD) is one of the most common mental disorders among the older
adults. Population aging, social stress, and the COVID-19 pandemic have significantly …
adults. Population aging, social stress, and the COVID-19 pandemic have significantly …
[HTML][HTML] Omega-3 fatty acids for inflamed depression–A match/mismatch study
K Suneson, GS Veibäck, J Lindahl, J Tjernberg… - Brain, Behavior, and …, 2024 - Elsevier
Despite decades of research on the pathophysiology of depression, the development of new
therapeutic interventions has been slow, and no biomarkers of treatment response have …
therapeutic interventions has been slow, and no biomarkers of treatment response have …
A longitudinal study of distress symptoms and work impairment in immune-mediated inflammatory diseases
Objective We investigated the association between distress symptoms (pain, fatigue,
depression, anxiety) and work impairment in four patient populations: multiple sclerosis (N …
depression, anxiety) and work impairment in four patient populations: multiple sclerosis (N …
Young adults with major depression show altered microbiome
There is growing basic and clinical evidence that major depressive disorder (MDD) is
associated with gut microbiome alterations, but clinical studies have tended not to adjust for …
associated with gut microbiome alterations, but clinical studies have tended not to adjust for …
[HTML][HTML] Inflammatory depression is associated with selective glomerular hypofiltration
GS Veibäck, L Malmgren, M Asp, F Ventorp… - Journal of Affective …, 2024 - Elsevier
Background Systemic low-grade inflammation may be a pathophysiological mechanism in a
subtype of depression. In this study we investigate a novel candidate mechanism of …
subtype of depression. In this study we investigate a novel candidate mechanism of …
Association between Dietary Antioxidant Capacity in Midlife and Depressive Symptoms in Late Life: The Singapore Chinese Health Study
Preclinical and limited epidemiological studies suggest that oxidative stress may be
implicated in geriatric depression. Our study investigated the association between midlife …
implicated in geriatric depression. Our study investigated the association between midlife …
Clinical symptoms and their relationship with cognitive impairment in elderly patients with depressive disorder
Z Wu, G Su, W Lu, L Liu, Z Zhou, B Xie - Frontiers in Psychiatry, 2022 - frontiersin.org
Objective To evaluate the correlation between clinical symptoms and cognitive impairment
in elderly patients with depressive disorder. Methods In this retrospective study, a total of …
in elderly patients with depressive disorder. Methods In this retrospective study, a total of …
Analysis of the prescribing pattern of antidepressants and the side effects in depression patients
SK Ara - Journal of family medicine and primary care, 2022 - journals.lww.com
Major depressive disorder (MDD) is a mental disorder characterized by impairment in mood
regulation, loss of interest or pleasure, feelings of guilt, low self-worth, disturbed sleep and …
regulation, loss of interest or pleasure, feelings of guilt, low self-worth, disturbed sleep and …
Developing prediction algorithms for late-life depression using wearable devices: a cohort study protocol
Introduction Despite the high prevalence of major depressive disorder (MDD) among the
elderly population, the rate of treatment is low due to stigmas and barriers to medical access …
elderly population, the rate of treatment is low due to stigmas and barriers to medical access …