Liquid biopsy of methylation biomarkers in cell-free DNA
H Luo, W Wei, Z Ye, J Zheng, R Xu - Trends in molecular medicine, 2021 - cell.com
Liquid biopsies, in particular, analysis of cell-free DNA (cfDNA), have emerged as a
promising noninvasive diagnostic approach in oncology. Abnormal distribution of DNA …
promising noninvasive diagnostic approach in oncology. Abnormal distribution of DNA …
Liquid biopsy at the frontier in renal cell carcinoma: recent analysis of techniques and clinical application
M Li, L Li, J Zheng, Z Li, S Li, K Wang, X Chen - Molecular Cancer, 2023 - Springer
Renal cell carcinoma (RCC) is a major pathological type of kidney cancer and is one of the
most common malignancies worldwide. The unremarkable symptoms of early stages …
most common malignancies worldwide. The unremarkable symptoms of early stages …
Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes
Improving early cancer detection has the potential to substantially reduce cancer-related
mortality. Cell-free methylated DNA immunoprecipitation and high-throughput sequencing …
mortality. Cell-free methylated DNA immunoprecipitation and high-throughput sequencing …
Tumor fractions deciphered from circulating cell-free DNA methylation for cancer early diagnosis
X Zhou, Z Cheng, M Dong, Q Liu, W Yang, M Liu… - Nature …, 2022 - nature.com
Tumor-derived circulating cell-free DNA (cfDNA) provides critical clues for cancer early
diagnosis, yet it often suffers from low sensitivity. Here, we present a cancer early diagnosis …
diagnosis, yet it often suffers from low sensitivity. Here, we present a cancer early diagnosis …
Clinical utility of cell-free and circulating tumor DNA in kidney and bladder cancer: a critical review of current literature
EA Green, R Li, L Albiges, TK Choueiri… - European urology …, 2021 - Elsevier
Context Bladder and kidney cancers require invasive procedures for definitive diagnosis,
and bladder cancer requires repeated procedures to monitor for disease recurrence. Given …
and bladder cancer requires repeated procedures to monitor for disease recurrence. Given …
Detecting neuroendocrine prostate cancer through tissue-informed cell-free DNA methylation analysis
Purpose: Neuroendocrine prostate cancer (NEPC) is a resistance phenotype that emerges
in men with metastatic castration-resistant prostate adenocarcinoma (CR-PRAD) and has …
in men with metastatic castration-resistant prostate adenocarcinoma (CR-PRAD) and has …
Cell-free DNA-methylation-based methods and applications in oncology
F Galardi, F De Luca, D Romagnoli, C Biagioni… - Biomolecules, 2020 - mdpi.com
Liquid biopsy based on cell-free DNA (cfDNA) enables non-invasive dynamic assessment of
disease status in patients with cancer, both in the early and advanced settings. The analysis …
disease status in patients with cancer, both in the early and advanced settings. The analysis …
Update on biomarkers in renal cell carcinoma
Immune checkpoint inhibitors have significantly transformed the treatment paradigm for
metastatic renal cell carcinoma (RCC), offering prolonged overall survival and achieving …
metastatic renal cell carcinoma (RCC), offering prolonged overall survival and achieving …
Liquid biopsy from research to clinical practice: focus on non-small cell lung cancer
Introduction In the current era of personalized medicine, liquid biopsy has acquired a
relevant importance in patient management of advanced stage non-small cell lung cancer …
relevant importance in patient management of advanced stage non-small cell lung cancer …
Management of renal cell carcinoma: promising biomarkers and the challenges to reach the clinic
I Lyskjær, L Iisager, CT Axelsen, TK Nielsen… - Clinical Cancer …, 2024 - AACR
The incidence of renal cell carcinoma (RCC) is increasing worldwide, yet research within
this field is lagging behind other cancers. Despite increased detection of early disease as a …
this field is lagging behind other cancers. Despite increased detection of early disease as a …