Chasing molecules that were never there: misassigned natural products and the role of chemical synthesis in modern structure elucidation
KC Nicolaou, SA Snyder - Angewandte Chemie International …, 2005 - Wiley Online Library
Over the course of the past half century, the structural elucidation of unknown natural
products has undergone a tremendous revolution. Before World War II, a chemist would …
products has undergone a tremendous revolution. Before World War II, a chemist would …
Marine natural products
Covering: 2003. Previous review: Nat. Prod. Rep., 2004, 21, 1 This review covers the
literature published in 2003 for marine natural products, with 619 citations (413 for the …
literature published in 2003 for marine natural products, with 619 citations (413 for the …
Isolation, chemical, and biotransformation routes of labdane-type diterpenes
LMT Frija, RFM Frade, CAM Afonso - Chemical reviews, 2011 - ACS Publications
Small molecule natural products continue to provide an incomparable source of inspiration
for advances in organic chemistry and disease treatment. 1Ā6 Labdane-type diterpenes are …
for advances in organic chemistry and disease treatment. 1Ā6 Labdane-type diterpenes are …
Spongian diterpenoids from marine sponges
RA Keyzers, PT Northcote… - Natural Product …, 2006 - pubs.rsc.org
Covering: up to the end of 2004 This review presents the structure, biological activity and,
where applicable, references to the syntheses of 154 spongian and rearranged spongian …
where applicable, references to the syntheses of 154 spongian and rearranged spongian …
Die Jagd auf Moleküle, die nie existiert haben: Falsch zugeordnete Naturstoffstrukturen und die Rolle der chemischen Synthese in der modernen Strukturaufklärung
KC Nicolaou, SA Snyder - Angewandte Chemie, 2005 - Wiley Online Library
Abstract Im Laufe der vergangenen 50 Jahre hat hinsichtlich der Aufklärung der Strukturen
unbekannter Naturstoffe eine gewaltige Umwälzung stattgefunden. In der ersten Hälfte des …
unbekannter Naturstoffe eine gewaltige Umwälzung stattgefunden. In der ersten Hälfte des …
Spongiane diterpenoids
MA Gonzalez - Current bioactive compounds, 2007 - ingentaconnect.com
In this review we cover the structures, occurrence, biological activities and synthesis of all
the spongianes and rearranged spongianes since their discovery in 1974. We have given …
the spongianes and rearranged spongianes since their discovery in 1974. We have given …
Short syntheses of (+)-ferruginol from (+)-dehydroabietylamine
MA González, D Pérez-Guaita - Tetrahedron, 2012 - Elsevier
Short syntheses of bioactive (+)-ferruginol in five or six synthetic steps starting from
commercially available (+)-dehydroabietylamine are described. The oxygenated function at …
commercially available (+)-dehydroabietylamine are described. The oxygenated function at …
Norrisolide: total synthesis and related studies
TP Brady, SH Kim, K Wen, C Kim… - … –A European Journal, 2005 - Wiley Online Library
Abstract A stereoselective synthesis of (+)‐norrisolide is presented. This natural product
belongs to a family of marine spongiane diterpenes the structure of which is characterized …
belongs to a family of marine spongiane diterpenes the structure of which is characterized …
Enantio-and diastereoselective synthesis of tetrahydrofuro [2, 3-b] furan-2 (3H)-one derivatives and related oxygen heterocycles via an asymmetric organocatalytic …
WW Zhao, YK Liu - Organic Chemistry Frontiers, 2017 - pubs.rsc.org
Tetrahydrofuro [2, 3-b] furan-2 (3H)-one derivatives bearing four stereogenic centers were
achieved via an asymmetric organocatalytic cascade process with excellent stereoselectivity …
achieved via an asymmetric organocatalytic cascade process with excellent stereoselectivity …
Divergent synthesis and chemical reactivity of bicyclic lactone fragments of complex rearranged spongian diterpenes
MJ Schnermann, CM Beaudry… - Journal of the …, 2011 - ACS Publications
The synthesis and direct comparison of the chemical reactivity of the two highly oxidized
bicyclic lactone fragments found in rearranged spongian diterpenes (8-substituted 6-acetoxy …
bicyclic lactone fragments found in rearranged spongian diterpenes (8-substituted 6-acetoxy …