Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the
death of both upper and lower motor neurons (MNs) in the brain, brainstem and spinal cord …

Amyotrophic lateral sclerosis (ALS) is a lethal disease, characterized by progressive death
of motor neurons with unknown etiology. Evidence from animal models indicates that …

One of the crucial systems severely affected in several neuromuscular diseases is the loss of
effective connection between muscle and nerve, leading to a pathological non …

Amyotrophic lateral sclerosis (ALS), the major adult-onset motor neuron disease, has been
viewed almost exclusively as a disease of upper and lower motor neurons, with muscle …

Amyotrophic lateral sclerosis (ALS) is a motor neuron disease with an extremely
heterogeneous clinical and genetic phenotype. In our efforts to find therapies for ALS, the …

Neurodegenerative diseases have been intensively studied, but a comprehensive
understanding of their pathogenesis remains elusive. An increasing body of evidence …

The clinical manifestation of most diseases of the central nervous system results from
neuronal dysfunction or loss. Diseases such as stroke, epilepsy and neurodegeneration (eg …

Growth factors in the brain are important to depression and it's treatment and we assessed
the ability of peripherally administered insulin-like growth factor-I (IGF-I) to influence …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with
motor neuron degeneration, muscle atrophy and paralysis. Although numerous pathological …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with
motor neuron degeneration, muscle weakness, paralysis and finally death. The proposed …