Disorders of the synovial joint, such as osteoarthritis (OA) and rheumatoid arthritis (RA),
afflict a substantial proportion of the global population. However, current clinical …

The expeditious advancement in the organ on chip technology provided a phase change to
the conventional in vitro tests used to evaluate absorption, distribution, metabolism …

Abstract 3D printing has emerged as one of the most promising tools to overcome the
processing and morphological limitations of traditional tissue engineering scaffold design …

An accurate in vitro model of human adipose tissue could assist in the study of adipocyte
function and allow for better tools for screening new therapeutic compounds. Cell culture …

Obesity and associated diseases, such as diabetes, have reached epidemic proportions
globally. In this era of “diabesity”, white adipose tissue (WAT) has become a target of high …

The obesity epidemic and its associated comorbidities present a looming challenge to
health care delivery throughout the world. Obesity is characterized as a sterile inflammatory …

Subcutaneous (subQ) injection is a common route for delivering biotherapeutics, wherein
pharmacokinetics is largely influenced by drug transport in a complex subQ tissue …

Organs-on-chips, also known as “tissue chips” or microphysiological systems (MPS), are
bioengineered microsystems capable of recreating aspects of human organ physiology and …

Microphysiological systems (MPS) are promising in vitro tools which could substantially
improve the drug development process, particularly for underserved patient populations …

Mesenchymal stem cells (MSCs) are multipotent stromal cells, with the ability to differentiate
into mesodermal (eg, adipocyte, chondrocyte, hematopoietic, myocyte, osteoblast) …