Diabetic retinopathy is a major retinal disease and a leading cause of blindness in the world.
Diabetic retinopathy is a neurovascular disease that is associated with disturbances of the …

Neurodegeneration plays a significant role in the complex pathology of diabetic retinopathy.
Evidence suggests the onset of neurodegeneration occurs early on in the disease, and so a …

NADPH oxidases (NOXs) are major players in generating reactive oxygen species (ROS)
and are implicated in various neurodegenerative ocular pathologies. The aim of this study …

The endocannabinoid system (ECS) is a new target for the development of retinal disease
therapeutics, whose pathophysiology involves neurodegeneration and neuroinflammation …

Diabetic retinopathy (DR) is the most common microvascular complication in diabetes and
may cause severe visual impairment. Until late stages of DR, treatment options are limited …

Hyperglycemia-induced oxidative stress plays a key role in the impairment of the retinal
neurovascular unit, an early event in the pathogenesis of DR. The aim of this study was to …

Microneurotrophins, small-molecule mimetics of endogenous neurotrophins, have
demonstrated significant therapeutic effects on various animal models of neurological …

Oxidative stress, neurodegeneration, neuroinflammation, and vascular leakage are believed
to play a key role in the early stage of diabetic retinopathy (ESDR). The aim of this study was …

Glutamate excitotoxicity and oxidative stress represent two major pathological mechanisms
implicated in retinal disorders. In Diabetic Retinopathy (DR), oxidative stress is correlated to …

BNN27 is a novel 17‐spiroepoxy derivative of the neurosteroid Dehydroepiandrosterone
with neuroprotective properties. The purpose of this study was the detection and …