Trillions of microbes survive and thrive inside the human body. These tiny creatures are
crucial to the development and maturation of our immune system and to maintain gut …

Aging and various age-related diseases are associated with reductions in melatonin
secretion, proinflammatory changes in the immune system, a deteriorating circadian system …

Mesenchymal stem cell (MSC)–derived exosome plays a central role in the cell-free
therapeutics involving MSCs and the contents can be customized under disease-associated …

MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

Lung cancer is the leading cause of malignancy-related incidence and mortality worldwide.
Molecular mechanisms underlying tumorigenesis and development of lung cancer are still …

The efficacy of macrophage-mediated inflammatory response relies on the coordinated
expression of key factors, which expression is finely regulated at both transcriptional and …

Mammals exist in a complicated symbiotic relationship with their gut microbiome, which is
postulated to have broad impacts on host health and disease. As omics-based technologies …

Macrophages and microglia play crucial roles during central nervous system development,
homeostasis and acute events such as infection or injury. The diverse functions of tissue …

Neural stem cell (NSC) grafting in conditions such as aging, brain injury, and
neurodegenerative diseases promotes regeneration, plasticity and functional recovery …

Emerging evidence indicates that cancer cell-derived exosomes contribute to cancer
progression through the modulation of tumor microenvironment, but the underlying …