LncRNAs in ovarian cancer progression, metastasis, and main pathways: ceRNA and alternative mechanisms

EA Braga, MV Fridman, AA Moscovtsev… - International journal of …, 2020 - mdpi.com
Ovarian cancer (OvCa) develops asymptomatically until it reaches the advanced stages with
metastasis, chemoresistance, and poor prognosis. Our review focuses on the analysis of …

RNA modifications and cancer

P Haruehanroengra, YY Zheng, Y Zhou, Y Huang… - RNA biology, 2020 - Taylor & Francis
ABSTRACT RNA plays essential roles in not only translating nucleic acids into proteins, but
also in gene regulation, environmental interactions and many human diseases. Nature uses …

Influence of benzo (a) pyrene on different epigenetic processes

B Bukowska, P Sicińska - International Journal of Molecular Sciences, 2021 - mdpi.com
Epigenetic changes constitute one of the processes that is involved in the mechanisms of
carcinogenicity. They include dysregulation of DNA methylation processes, disruption of …

[HTML][HTML] Targeting miRNAs by natural products: A new way for cancer therapy

B Zhang, L Tian, J Xie, G Chen, F Wang - Biomedicine & Pharmacotherapy, 2020 - Elsevier
MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression through
mRNA degradation or translation inhibition. MiRNAs play important roles in a variety of …

Molecular mechanisms and microRNAs in osteosarcoma pathogenesis

NE Kushlinskii, MV Fridman, EA Braga - Biochemistry (Moscow), 2016 - Springer
This review summarizes data on microRNA (miRNA) genomic organization, biogenesis, and
functions in carcinogenesis. The roles of key genes and regulatory miRNAs in molecular …

Molecular mechanisms in clear cell renal cell carcinoma: role of miRNAs and hypermethylated miRNA genes in crucial oncogenic pathways and processes

EA Braga, MV Fridman, VI Loginov, AA Dmitriev… - Frontiers in …, 2019 - frontiersin.org
Clear cell renal cell carcinoma (ccRCC) is the third most common urological cancer, and it
has the highest mortality rate. The increasing drug resistance of metastatic ccRCC has …

Novel miRNA genes deregulated by aberrant methylation in ovarian carcinoma are involved in metastasis

VI Loginov, IV Pronina, AM Burdennyy, EA Filippova… - Gene, 2018 - Elsevier
Methylation of promoter CpG islands may suppress the function of miRNAs by inhibiting their
expression. Our work analyzes the role of promoter methylation in altering the expression of …

[HTML][HTML] The role of microRNA in the resistance to treatment of hepatocellular carcinoma

MY Pratama, D Pascut, MN Massi… - Annals of translational …, 2019 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the second most common cause of cancer-related death
with a limited efficacy of treatment for intermediate and advanced stages of the disease …

MicroRNA as epigenetic modifiers in endometrial cancer: a systematic review

A Favier, G Rocher, AK Larsen, R Delangle, C Uzan… - Cancers, 2021 - mdpi.com
Simple Summary Endometrial cancer (EC) is the 2nd most common gynecologic cancer
worldwide. MicroRNAs (miRNAs) are small noncoding RNAs that contribute to epigenetic …

miR‐145 promotes miR‐133b expression through c‐myc and DNMT3A‐mediated methylation in ovarian cancer cells

J Li, S Zhang, Y Zou, L Wu, M Pei… - Journal of cellular …, 2020 - Wiley Online Library
Ovarian cancer presents as malignant tumors in the female reproductive system with high
mortality. MicroRNAs are involved in the progression of ovarian cancer; however, the …