Hemophagocytic lymphohistiocytosis: current treatment advances, emerging targeted therapy and underlying mechanisms
Y Wu, X Sun, K Kang, Y Yang, H Li, A Zhao… - Journal of Hematology & …, 2024 - Springer
Hemophagocytic lymphohistiocytosis (HLH) is a rapidly progressing, life-threatening
syndrome characterized by excessive immune activation, often presenting as a complex …
syndrome characterized by excessive immune activation, often presenting as a complex …
Hemophagocytic lymphohistiocytosis and macrophage activation syndrome: two rare sides of the same devastating coin
F Sztajnbok, AR Fonseca, LR Campos… - Advances in …, 2024 - SciELO Brasil
Hemophagocytic lymphohistiocytosis (HLH) is a rare genetic hyperinflammatory syndrome
that occurs early in life. Macrophage activation syndrome (MAS) usually refers to a …
that occurs early in life. Macrophage activation syndrome (MAS) usually refers to a …
Efficacy of T-cell assays for the diagnosis of primary defects in cytotoxic lymphocyte exocytosis
Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated
with autosomal recessive variants in genes required for perforin-mediated lymphocyte …
with autosomal recessive variants in genes required for perforin-mediated lymphocyte …
GATA2 deficiency and hemophagocytic lymphohistiocytosis (HLH): a systematic review of reported cases
MRZ Rukerd, H Mirkamali, M Nakhaie… - BMC infectious …, 2024 - Springer
Purpose GATA2 deficiency is an autosomal dominant disease that manifests with a range of
clinical symptoms, including increased susceptibility to viral, bacterial, and fungal infections …
clinical symptoms, including increased susceptibility to viral, bacterial, and fungal infections …
Comprehensive insights into tuberculosis-associated hemophagocytic lymphohistiocytosis: a systematic review
A Eslami, S Alimoghadam, S Khodadadi… - BMC Infectious …, 2024 - Springer
Background Tuberculosis-associated hemophagocytic lymphohistiocytosis (TB-HLH)
presents significant challenges in diagnosis and treatment due to its complex interplay …
presents significant challenges in diagnosis and treatment due to its complex interplay …
A Novel Engineering Cell Therapy Platform Mimicking the Immune Thrombocytopenia‐Derived Platelets to Inhibit Cytokine Storm in Hemophagocytic …
Z Liu, Y Du, T Zhou, T Qin, Y Yuan, W Xu… - Advanced …, 2024 - Wiley Online Library
Hemophagocytic lymphohistiocytosis (HLH) is a common and highly fatal hyperinflammatory
syndrome characterized by the aberrant activation of macrophages. To date, there is a lack …
syndrome characterized by the aberrant activation of macrophages. To date, there is a lack …
Clinical and biological advances of critical complications in acute myeloid leukemia
A Costa, E Scalzulli, I Carmosino, C Ielo… - Leukemia & …, 2024 - Taylor & Francis
Managing acute myeloid leukemia (AML) and its critical complications requires
understanding the complex interplay between disease biology, treatment strategies, and …
understanding the complex interplay between disease biology, treatment strategies, and …
[HTML][HTML] Hemophagocytic Lymphohistiocytosis Triggered by Herpes Simplex Virus 1 and 2: A Narrative Review
A Papazachariou, P Ioannou - Hematology Reports, 2024 - mdpi.com
Introduction: Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening syndrome
characterized by an uncontrolled hyperinflammatory reaction. HLH is classified into primary …
characterized by an uncontrolled hyperinflammatory reaction. HLH is classified into primary …
Case reports as early safety signals: learning from the COVID-19 vaccination campaign
M Goldman, RE Chandler - Frontiers in Medicine, 2024 - frontiersin.org
The development of anti-SARS-CoV-2 vaccines will stay as a landmark in the history of
modern medicine, both as a major scientific achievement and an unprecedented public …
modern medicine, both as a major scientific achievement and an unprecedented public …
Macrophage Activation Syndrome in Children: Update on Diagnosis and Treatment
J Lee, KS Bae, JW Rhim, SY Lee, DC Jeong, JH Kang - Children, 2024 - mdpi.com
Macrophage activation syndrome (MAS) is potentially fatal; so, early diagnosis and timely
treatment are essential. However, detecting MAS is sometimes challenging because its …
treatment are essential. However, detecting MAS is sometimes challenging because its …