Targeting Th17 cells in HIV-1 remission/cure interventions

A Fert, LR Marchand, TRW Salinas, P Ancuta - Trends in Immunology, 2022 - cell.com
Since the discovery of HIV-1, progress has been made in deciphering the viral replication
cycle and mechanisms of host–pathogen interactions that has facilitated the implementation …

HIV pathogenesis in the human female reproductive tract

M Rodriguez-Garcia, K Connors, M Ghosh - Current HIV/AIDS Reports, 2021 - Springer
Abstract Purpose of Review Women remain disproportionately affected by the HIV/AIDS
pandemic. The primary mechanism for HIV acquisition in women is sexual transmission, yet …

Pyroptosis associated with immune reconstruction failure in HIV-1-infected patients receiving antiretroviral therapy: a cross-sectional study

X Lao, X Mei, J Zou, Q Xiao, Q Ning, X Xu… - BMC Infectious …, 2022 - Springer
Background Highly active anti-retroviral therapy (HAART) can successfully suppress human
immunodeficiency virus (HIV) viral replication and reconstruct immune function …

Impact of tamoxifen on vorinostat-induced human immunodeficiency virus expression in women on antiretroviral therapy: AIDS Clinical Trials Group A5366, the MOXIE …

EP Scully, E Aga, A Tsibris, N Archin… - Clinical Infectious …, 2022 - academic.oup.com
Background Biological sex and the estrogen receptor alpha (ESR1) modulate human
immunodeficiency virus (HIV) activity. Few women have enrolled in clinical trials of latency …

Sex differences in HIV-1 persistence and the implications for a cure

S Rao - Frontiers in Global Women's Health, 2022 - frontiersin.org
Of the 38 million people currently living with Human Immunodeficiency Virus type-1 (HIV-1),
women, especially adolescents and young women, are disproportionally affected by the HIV …

Sex differences in cytokine profiles during suppressive antiretroviral therapy

C Vanpouille, A Wells, T Wilkin, JS Mathad, S Morris… - Aids, 2022 - journals.lww.com
Objective: Despite lower plasma HIV RNA levels, women progress faster to AIDS than men.
The reasons for these differences are not clear but might be a consequence of an elevated …

Impact of hormonal therapy on HIV‐1 immune markers in cis women and gender minorities

C Pasin, DG Nuñez, K Kusejko, A Hachfeld… - HIV …, 2024 - Wiley Online Library
Background Although sex hormones are recognized to induce immune variations, the effect
of hormonal therapy use on immunity is only poorly understood. Here, we quantified how …

A viral-specific CD4+ T cell response protects female mice from Coxsackievirus B3 infection

A Pattnaik, AH Dhalech, SA Condotta, C Corn… - Frontiers in …, 2024 - frontiersin.org
Background Biological sex plays an integral role in the immune response to various
pathogens. The underlying basis for these sex differences is still not well defined. Here, we …

Proteins in pregnant swine serum promote the African swine fever virus replication: an iTRAQ-based quantitative proteomic analysis

J Yang, X Yuan, Y Hao, X Shi, X Yang, W Yan, L Chen… - Virology Journal, 2023 - Springer
African swine fever (ASF) is a severe infectious disease caused by the African swine fever
virus (ASFV), seriously endangering the global pig industry. ASFV possesses a large …

[HTML][HTML] Phenotypic Characterization of Subtype A and Recombinant AC Transmitted/Founder Viruses from a Rwandan HIV-1 Heterosexual Transmission Cohort

L Yue, R Xu, S Mclnally, Q Qin, JW Rhodes, E Muok… - Viruses, 2024 - mdpi.com
HIV-1 subtypes have distinct geographical distributions, with subtypes A, C, and D and inter-
subtype recombinants circulating in sub-Saharan Africa. Historically, individuals living with …