Multicomponent transporters are used by bacteria to transport a wide range of nutrients.
These systems use a substrate-binding protein to bind the nutrient with high affinity and then …

RegulonDB is a database that contains the most comprehensive corpus of knowledge of the
regulation of transcription initiation of Escherichia coli K-12, including data from both …

Tripartite ATP-independent periplasmic (TRAP) transporters are nutrient-uptake systems
found in bacteria and archaea. These evolutionary divergent transporter systems couple a …

Adoptive cell therapies for solid tumors are usually limited by off-target antigens, incapable
tissue infiltration, and cell function exhaustion. In contrast, bacterial cells possess the …

Multi-wavelength analytical ultracentrifugation (MW-AUC) is a recent development made
possible by new analytical ultracentrifuge optical systems. MW-AUC extends the basic …

To adapt to changes in environmental cues, Pseudomonas aeruginosa produces an array of
virulence factors to survive the host immune responses during infection. Metabolic products …

Within the complex milieu of a cell, which comprises a large number of different
biomolecules, interactions are critical for function. In this post-reductionist era of biochemical …

Aim: We present multi-wavelength (MW) analytical ultracentrifugation (AUC) methods
offering superior accuracy for adeno-associated virus characterization and quantification …

The long non-coding RNAs (lncRNAs) other than rRNA and tRNA were earlier assumed to
be 'junk genomic material'. However, recent advancements in genomics methods have …

A key step in metabolic pathway evolution is the recruitment of promiscuous enzymes to
perform new functions. Despite the recognition that promiscuity is widespread in biology …