Gimme shelter: the immune system during pregnancy

A Munoz‐Suano, AB Hamilton… - Immunological reviews, 2011 - Wiley Online Library
Antigen‐presenting molecules vary between individuals of the same species, making it more
difficult for pathogens to evade immune recognition and spread through the whole …

Autophagy: a potential key contributor to the therapeutic action of mesenchymal stem cells

S Ceccariglia, A Cargnoni, AR Silini, O Parolini - Autophagy, 2020 - Taylor & Francis
Macroautophagy/autophagy occurs at basal levels in all eukaryotic cells and plays an
important role in maintaining bio-energetic homeostasis through the control of molecule …

Immunosuppressive properties of mesenchymal stem cells

M Abumaree, M Al Jumah, RA Pace… - Stem Cell Reviews and …, 2012 - Springer
Mesenchymal stem cells (MSC) can be isolated from different adult tissues including bone
marrow, adipose tissue, cord blood and placenta. MSCs modulate the immune function of …

Immunological aspects of allogeneic mesenchymal stem cell therapies

MD Griffin, T Ritter, BP Mahon - Human gene therapy, 2010 - liebertpub.com
Allogeneic mesenchymal stem or stromal cells (MSCs) are proposed as cell therapies for
degenerative, inflammatory, and autoimmune diseases. The feasibility of allogeneic MSC …

The long path of human placenta, and its derivatives, in regenerative medicine

AR Silini, A Cargnoni, M Magatti, S Pianta… - … in bioengineering and …, 2015 - frontiersin.org
In the 1800s, a baby born with a caul, a remnant of the amniotic sack or fetal membranes,
was thought to be lucky, special, or protected. Over time, fetal membranes lost their …

Mesenchymal stromal cell characteristics vary depending on their origin

H Wegmeyer, AM Bröske, M Leddin… - Stem cells and …, 2013 - liebertpub.com
Mesenchymal stromal cells (MSCs) are rare progenitor cells that can be isolated from
various tissues. They exhibit multilineage differentiation potential, support regenerative …

Mesenchymal stem/stromal cells: a new''cells as drugs''paradigm. Efficacy and critical aspects in cell therapy

L de Girolamo, E Lucarelli, G Alessandri… - Current …, 2013 - ingentaconnect.com
Mesenchymal stem cells (MSCs) were first isolated more than 50 years ago from the bone
marrow. Currently MSCs may also be isolated from several alternative sources and they …

Immunomodulatory properties of human adult and fetal multipotent mesenchymal stem cells

PM Chen, ML Yen, KJ Liu, HK Sytwu… - Journal of Biomedical …, 2011 - Springer
In recent years, a large number of studies have contributed to our understanding of the
immunomodulatory mechanisms used by multipotent mesenchymal stem cells (MSCs) …

The immunomodulatory properties of amniotic cells: the two sides of the coin

M Magatti, E Vertua, A Cargnoni, A Silini… - Cell …, 2018 - journals.sagepub.com
Among the many cell types useful in developing therapeutic treatments, human amniotic
cells from placenta have been proposed as valid candidates. Both human amniotic epithelial …

Amniotic membrane mesenchymal cells-derived factors skew T cell polarization toward Treg and downregulate Th1 and Th17 cells subsets

S Pianta, P Bonassi Signoroni, I Muradore… - Stem Cell Reviews and …, 2015 - Springer
We previously demonstrated that cells derived from the mesenchymal layer of the human
amniotic membrane (hAMSC) and their conditioned medium (CM-hAMSC) modulate …