The control of sleep and wakefulness by mesolimbic dopamine systems
The mesolimbic dopamine pathway between the ventral tegmental area (VTA) and the
nucleus accumbens (NAc) plays a central role in motivational behaviors. Recent findings …
nucleus accumbens (NAc) plays a central role in motivational behaviors. Recent findings …
HIV-associated executive dysfunction in the era of modern antiretroviral therapy: A systematic review and meta-analysis
KA Walker, GG Brown - Journal of clinical and experimental …, 2018 - Taylor & Francis
Objective: While some reports suggest that HIV+ individuals continue to display executive
function (EF) impairment in the era of cART, findings have been contradictory and appear to …
function (EF) impairment in the era of cART, findings have been contradictory and appear to …
[HTML][HTML] Nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine D1 receptors
Nucleus accumbens (NAc) is involved in behaviors that depend on heightened wakefulness,
but its impact on arousal remains unclear. Here, we demonstrate that NAc dopamine D1 …
but its impact on arousal remains unclear. Here, we demonstrate that NAc dopamine D1 …
Deficits in mesolimbic reward pathway underlie social interaction impairments in children with autism
Lack of interest in social interaction is a hallmark of autism spectrum disorder. Animal
studies have implicated the mesolimbic reward pathway in driving and reinforcing social …
studies have implicated the mesolimbic reward pathway in driving and reinforcing social …
Repetitive behaviors in autism are linked to imbalance of corticostriatal connectivity: a functional connectivity MRI study
The neural underpinnings of repetitive behaviors (RBs) in autism spectrum disorders
(ASDs), ranging from cognitive to motor characteristics, remain unknown. We assessed RB …
(ASDs), ranging from cognitive to motor characteristics, remain unknown. We assessed RB …
[HTML][HTML] Evidence and explanation for the involvement of the nucleus accumbens in pain processing
HN Harris, YB Peng - Neural regeneration research, 2020 - journals.lww.com
The nucleus accumbens (NAc) is a subcortical brain structure known primarily for its roles in
pleasure, reward, and addiction. Despite less focus on the NAc in pain research, it also …
pleasure, reward, and addiction. Despite less focus on the NAc in pain research, it also …
Synaptic and cellular endocannabinoid signaling mechanisms regulate stress-induced plasticity of nucleus accumbens somatostatin neurons
Interneuron populations within the nucleus accumbens (NAc) orchestrate excitatory-
inhibitory balance, undergo experience-dependent plasticity, and gate-motivated behavior …
inhibitory balance, undergo experience-dependent plasticity, and gate-motivated behavior …
[HTML][HTML] GABAergic neurons in nucleus accumbens are correlated to resilience and vulnerability to chronic stress for major depression
Background Major depression, persistent low mood, is one of common psychiatric diseases.
Chronic stressful life is believed to be a major risk factor that leads to dysfunctions of the …
Chronic stressful life is believed to be a major risk factor that leads to dysfunctions of the …
Motivational competition and the paraventricular thalamus
GP McNally - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Although significant progress has been made in understanding the behavioral and brain
mechanisms for motivational systems, much less is known about competition between …
mechanisms for motivational systems, much less is known about competition between …
The food and drug addiction epidemic: targeting dopamine homeostasis
Obesity is damaging the lives of more than 300 million people worldwide and maintaining a
healthy weight using popular weight loss tactics remains a very difficult undertaking …
healthy weight using popular weight loss tactics remains a very difficult undertaking …