Viruses have been present during all evolutionary steps on earth and have had a major
effect on human history. Viral infections are still among the leading causes of death. Another …

Coxsackieviruses-induced infections, particularly in infants and young children, are one of
the most important public health issues in low-and middle-income countries, where the …

Coxsackievirus B (CVB) infection of pancreatic β cells is associated with β cell autoimmunity
and type 1 diabetes. We investigated how CVB affects human β cells and anti-CVB T cell …

Background Molecular mimicry is hypothesized to be a mechanism by which autoimmune
diseases are triggered. It refers to sequence or structural homology between foreign …

Type 1 diabetes (T1D) is a chronic autoimmune disease that attacks the insulin-producing b
cells of the pancreatic islets. Autoantibodies to b cell proteins typically appear in the …

Enteroviruses (EVs) are the most prevalent viruses in humans. EVs can cause a range of
acute symptoms, from mild common colds to severe systemic infections such as meningitis …

Type 1 diabetes (T1D) is a complex metabolic autoimmune disorder that affects millions of
individuals worldwide and often leads to significant comorbidities. However, the precise …

What triggers type 1 diabetes mellitus (T1DM)? One common assumption is that triggers are
individual microbes that mimic autoantibody targets such as insulin (INS). However, most …

Coxsackieviruses (CVs) are common causes of infections and can be life-threatening.
Unfortunately, rigorous studies guiding the clinician in interpreting CV serum antibody titer …

Interferon (IFN)-α is the earliest cytokine signature observed in individuals at risk for type 1
diabetes (T1D), but its effect on the repertoire of HLA Class I (HLA-I)-bound peptides …