Hollow microneedles: A perspective in biomedical applications

Á Cárcamo-Martínez, B Mallon… - International journal of …, 2021 - Elsevier
Microneedles (MN) have the potential to become a highly progressive device for both drug
delivery and monitoring purposes as they penetrate the skin and pierce the stratum corneum …

[HTML][HTML] Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development

E Larrañeta, REM Lutton, AD Woolfson… - Materials Science and …, 2016 - Elsevier
Transdermal drug delivery offers a number of advantages for the patient, due not only its non-
invasive and convenient nature, but also factors such as avoidance of first pass metabolism …

A fully integrated closed‐loop system based on mesoporous microneedles‐iontophoresis for diabetes treatment

X Li, X Huang, J Mo, H Wang, Q Huang… - Advanced …, 2021 - Wiley Online Library
A closed‐loop system that can mini‐invasively track blood glucose and intelligently treat
diabetes is in great demand for modern medicine, yet it remains challenging to realize …

Microneedle-mediated vaccination: innovation and translation

T Sheng, B Luo, W Zhang, X Ge, J Yu, Y Zhang… - Advanced drug delivery …, 2021 - Elsevier
Vaccine administration by subcutaneous or intramuscular injection is the most commonly
prescribed route for inoculation, however, it is often associated with some deficiencies such …

Wearable contact lens biosensors for continuous glucose monitoring using smartphones

M Elsherif, MU Hassan, AK Yetisen, H Butt - ACS nano, 2018 - ACS Publications
Low-cost, robust, and reusable continuous glucose monitoring systems that can provide
quantitative measurements at point-of-care settings is an unmet medical need. Optical …

Advances in transdermal insulin delivery

Y Zhang, J Yu, AR Kahkoska, J Wang, JB Buse… - Advanced drug delivery …, 2019 - Elsevier
Insulin therapy is necessary to regulate blood glucose levels for people with type 1 diabetes
and commonly used in advanced type 2 diabetes. Although subcutaneous insulin …

Recent advances of controlled drug delivery using microfluidic platforms

ST Sanjay, W Zhou, M Dou, H Tavakoli, L Ma… - Advanced drug delivery …, 2018 - Elsevier
Conventional systematically-administered drugs distribute evenly throughout the body, get
degraded and excreted rapidly while crossing many biological barriers, leaving minimum …

Sampling dermal interstitial fluid using microneedles: a review of recent developments in sampling methods and microneedle‐based biosensors

KM Saifullah, Z Faraji Rad - Advanced Materials Interfaces, 2023 - Wiley Online Library
Although interstitial fluid (ISF) is recognized as an important source of biomarkers, it is
difficult and time‐consuming to extract, thus limiting its use in medical diagnostic and clinical …

An overview of clinical and commercial impact of drug delivery systems

AC Anselmo, S Mitragotri - Journal of Controlled Release, 2014 - Elsevier
Drug delivery systems are widely researched and developed to improve the delivery of
pharmaceutical compounds and molecules. The last few decades have seen a marked …

Microneedles in the clinic

S Bhatnagar, K Dave, VVK Venuganti - Journal of controlled release, 2017 - Elsevier
In general, there is a profound influence of reducing physical dimensions of particulates and
devices on their physico-chemical and biological properties, and their performance …