Pharmacokinetics and bioavailability enhancement of baicalin: a review

T Huang, Y Liu, C Zhang - European Journal of Drug Metabolism and …, 2019 - Springer
Baicalin is one of the major bioactive components of Scutellaria radix, a Chinese herb that
has been used since ancient times. Baicalin has various pharmacological activities …

Pharmacological effects and pharmacokinetics properties of Radix Scutellariae and its bioactive flavones

C Li, G Lin, Z Zuo - Biopharmaceutics & drug disposition, 2011 - Wiley Online Library
Radix Scutellariae is the dried root of the medicinal plant Scutellariae baicalensis Georgi. It
exhibits a variety of therapeutic effects and has a long history of application in traditional …

The anti-inflammation effect of baicalin on experimental colitis through inhibiting TLR4/NF-κB pathway activation

L Cui, L Feng, ZH Zhang, XB Jia - International Immunopharmacology, 2014 - Elsevier
Background Baicalin holds a protective effect on inflammatory responses in several
diseases. However, its molecular mechanism of anti-inflammatory activity on ulcerative …

Regulatory mechanisms of baicalin in cardiovascular diseases: a review

L Xin, J Gao, H Lin, Y Qu, C Shang, Y Wang… - Frontiers in …, 2020 - frontiersin.org
Cardiovascular diseases (CVDs) is the leading cause of high morbidity and mortality
worldwide, which emphasizes the urgent necessity to develop new pharmacotherapies. In …

Antiviral properties of baicalin: A concise review

K Li, Y Liang, A Cheng, Q Wang, Y Li, H Wei… - Revista Brasileira de …, 2021 - Springer
Baicalin is one of the bioactive flavonoid glycosides isolated from the dried root of
Scutellaria baicalensis Georgi, Lamiaceae, with antiviral properties. In recent years, the …

Baicalin, an emerging multi-therapeutic agent: pharmacodynamics, pharmacokinetics, and considerations from drug development perspectives

NR Srinivas - Xenobiotica, 2010 - Taylor & Francis
Baicalin was extensively researched for utility in a number of therapeutic areas owing to its
anti-inflammatory, anti-oxidant, anti-bacterial, and anti-cancer properties. A number of …

Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, oroxylin A and chrysin of Radix scutellariae extract in rat plasma by liquid chromatography …

L Tong, M Wan, L Zhang, Y Zhu, H Sun, K Bi - Journal of pharmaceutical …, 2012 - Elsevier
A liquid chromatography tandem mass spectrometry (LC–MS/MS) method was developed
for the simultaneous determination of baicalin, wogonoside, baicalein, wogonin, oroxylin A …

Huang-Lian Jie-Du decoction: a review on phytochemical, pharmacological and pharmacokinetic investigations

Y Qi, Q Zhang, H Zhu - Chinese medicine, 2019 - Springer
Abstract Huang-Lian Jie-Du decoction (HLJDD), a famous traditional Chinese prescription
constituted by Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri and Fructus …

Flavones from root of Scutellaria baicalensis Georgi: drugs of the future in neurodegeneration?

K Gasiorowski, E Lamer-Zarawska… - CNS & Neurological …, 2011 - ingentaconnect.com
Flavonoids are natural, plant-derived compounds which exert diverse biological activities,
also valuable neuroprotective actions within the brain and currently are intensively studied …

[HTML][HTML] The Flavonoid components of Scutellaria baicalensis: Biopharmaceutical properties and their improvement using nanoformulation techniques

J Wang, X Feng, Z Li, Y Liu, W Yang… - Current topics in …, 2023 - ncbi.nlm.nih.gov
Scutellaria baicalensis georgi, known as “Huangqin” in its dried root form, is a herb widely
used in traditional Chinese medicine for “clearing away heat, removing dampness, purging …