The Handbook of Pharmaceutical Manufacturing Formulations, Third Edition: Volume Two,
Uncompressed Solid Products is an authoritative and practical guide to the art and science …

In solution, amphoteric compounds exist in anionic, uncharged, zwitterionic and cationic
forms. The importance of zwitterionic drugs is currently under‐represented in the literature …

Purpose To revise the IVIVC considering the physiologically sound Finite Absorption Time
(FAT) and Finite Dissolution Time (FDT) concepts. Methods The estimates τ and τ d for FAT …

Since the publication of Lindenberg et al., which classified orally administered active
pharmaceutical ingredients (APIs) on the 2004 Essential Medicines List (EML) of the World …

Carthamus tinctorius L.(Safflower) is extensively used as a functional food and herbal
medicine, with its application closely associated with hydroxysafflor yellow A (HSYA) …

BACKGROUND The main objective of this study was to evaluate the safety and
antihypertensive activity of rapeseed peptides and to investigate their potential synergy with …

Purpose Despite no broad, direct evidence in humans, there is a potential concern that
surfactants alter active or passive drug intestinal permeation to modulate oral drug …

Both machine learning and physiologically-based pharmacokinetic models are becoming
essential components of the drug development process. Integrating the predictive …

Enalapril is an off-patent angiotensin-converting enzyme inhibitor for which no paediatric
age-appropriate formulation is commercially available in Europe, and enalapril maleate …

The aim of this research was the production of extrudates for the treatment of hypertension
and heart failure and the investigation of the degradation of the peptidomimetic drug …