Rheumatoid arthritis (RA) is a chronic systemic, autoimmune and inflammatory disease
represented as synovitis, pannus formation, adjacent bone erosions, and joint destruction …

Circulating blood monocytes supply peripheral tissues with macrophage and dendritic cell
(DC) precursors and, in the setting of infection, also contribute directly to immune defense …

Antibody-dependent cellular cytotoxicity (ADCC) is exerted by immune cells expressing
surface Fcγ receptors (FcγRs) against cells coated with antibody, such as virus-infected or …

Blood monocyte subpopulations have been defined in man initially, and the two major types
of monocytes are the CD14++ CD16− and the CD14+ CD16+ monocytes. These cells have …

The term “monocyte” implies a single, homogenous population of cells with uniform
physiology. Recent evidence from a number of laboratories indicates that it is likely that …

Circulating monocytes can be divided into classical (CM), intermediate (IM), and non-
classical monocytes (NCM), and the classical monocytes also contain CD56+ monocytes …

The active form of vitamin D, 1, 25-dihydroxyvitamin D3 (1, 25 [OH] 2D3) is a potent
immunomodulatory seco-steroid. We have demonstrated that several components of vitamin …

Aging is a major risk factor for developing severe COVID-19, but few detailed data are
available concerning immunological changes after infection in aged individuals. Here we …

Although the immunological complexity of the maternal-fetal interface is well appreciated,
the actual interaction of maternal immune cells and fetal trophoblasts is insufficiently …

Peripheral blood monocytes play a central role in the mononuclear phagocyte system by
providing a critical link between the bone marrow (BM), as major site of adult hematopoiesis …