Advances in Therapy for Refractory Epilepsy
L Jehi - Annual Review of Medicine, 2024 - annualreviews.org
Drug-resistant epilepsy (DRE) is defined as failure to achieve sustained seizure control with
adequate trials of two appropriate antiseizure medications (ASMs). DRE affects one-third of …
adequate trials of two appropriate antiseizure medications (ASMs). DRE affects one-third of …
Applications of magnetic resonance-guided laser interstitial thermal therapy in disconnective epilepsy surgery
Minimally invasive surgical techniques, such as MR-guided laser interstitial thermal therapy
(LITT), have emerged as promising alternatives to open disconnective surgeries in drug …
(LITT), have emerged as promising alternatives to open disconnective surgeries in drug …
Machine learning models for predicting seizure outcome after MR-guided laser interstitial thermal therapy in children
OBJECTIVE MR-guided laser interstitial thermal therapy (MRgLITT) is associated with lower
seizure-free outcome but better safety profile compared to open surgery. However, the …
seizure-free outcome but better safety profile compared to open surgery. However, the …
A multi‐center comparison of surgical techniques for corpus Callosotomy in pediatric drug‐resistant epilepsy
D Hansen, S Shandley, J Olaya, J Hauptman… - …, 2024 - Wiley Online Library
Objectives Corpus callosotomy (CC) is used to reduce seizures, primarily in patients with
generalized drug‐resistant epilepsy (DRE). The invasive nature of the procedure contributes …
generalized drug‐resistant epilepsy (DRE). The invasive nature of the procedure contributes …
Clinical outcomes of MR-guided laser interstitial thermal therapy corpus callosum ablation in drug-resistant epilepsy: a systematic review and meta-analysis
OBJECTIVE The goal of this systematic review and meta-analysis was to provide an
updated analysis of studies investigating outcomes, morbidity, and mortality associated with …
updated analysis of studies investigating outcomes, morbidity, and mortality associated with …
Corpus callosotomy for intractable epilepsy: a contemporary series of operative factors and the overall complication rate
M Motiwala, S Tambi, A Motiwala, M Dacus… - Journal of …, 2024 - thejns.org
OBJECTIVE Corpus callosotomy is an effective treatment for atonic seizures in patients with
medically refractory epilepsy. A large modern series of corpus callosotomies performed via …
medically refractory epilepsy. A large modern series of corpus callosotomies performed via …
The changing landscape of palliative epilepsy surgery for Lennox Gastaut Syndrome
Lennox Gastaut Syndrome (LGS) is characterized by drug-resistant epilepsy that typically
leads to decreased quality of life and deleterious neurodevelopmental comorbidities from …
leads to decreased quality of life and deleterious neurodevelopmental comorbidities from …
Outcomes after laser interstitial thermal ablation for temporal lobe epilepsy: a systematic review and meta-analysis
SA Alomar, RH Moshref, LH Moshref, AJ Sabbagh - Neurosurgical Review, 2023 - Springer
Epilepsy is a common condition that affects approximately 1% of the world's population, with
about one-third being refractory epilepsy. Temporal lobe epilepsy is the most common type …
about one-third being refractory epilepsy. Temporal lobe epilepsy is the most common type …
Approach, complications, and outcomes for 37 consecutive pediatric patients undergoing laser ablation for medically refractory epilepsy at Stanford Children's Health
MIB Guinle, T Johnstone, D Li, H Kaur… - Journal of …, 2023 - thejns.org
OBJECTIVE The objective of this study was to better understand the safety and efficacy of
laser interstitial thermal therapy (LITT) for children with medically refractory epilepsy …
laser interstitial thermal therapy (LITT) for children with medically refractory epilepsy …
Comparison of magnetic resonance‐guided laser interstitial thermal therapy corpus callosum ablation to open microsurgical corpus callosotomy: A single‐center …
Objective Corpus callosotomy (CC) is an important treatment for atonic seizures in patients
with generalized or multifocal drug‐resistant epilepsy (DRE). Traditionally, CC is performed …
with generalized or multifocal drug‐resistant epilepsy (DRE). Traditionally, CC is performed …