Epidemiology of sepsis in surgical patients

LJ Moore, FA Moore - Surgical Clinics of North America, 2012 - Elsevier
Despite advances in surgical critical care, sepsis among surgical patients continues to be a
common and serious problem. As the population ages, the incidence of sepsis in the United …

Early diagnosis and evidence-based care of surgical sepsis

LJ Moore, FA Moore - Journal of intensive care medicine, 2013 - journals.sagepub.com
Sepsis continues to be a common and serious problem among surgical patients. It is a
leading cause of both morbidity and mortality in the perioperative period. The early …

Evidence for persistent immune suppression in patients who develop chronic critical illness after sepsis

JA Stortz, TJ Murphy, SL Raymond, JC Mira, R Ungaro… - Shock, 2018 - journals.lww.com
Background: Many sepsis survivors develop chronic critical illness (CCI) and are assumed
to be immunosuppressed, but there is limited clinical evidence to support this. We sought to …

Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis

MKK Hollen, JA Stortz, D Darden, ML Dirain… - Critical Care, 2019 - Springer
Background Sepsis is an increasingly significant challenge throughout the world as one of
the major causes of patient morbidity and mortality. Central to the host immunologic …

Machine learning techniques to identify antimicrobial resistance in the intensive care unit

S Martínez-Agüero, I Mora-Jiménez, J Lérida-García… - Entropy, 2019 - mdpi.com
The presence of bacteria with resistance to specific antibiotics is one of the greatest threats
to the global health system. According to the World Health Organization, antimicrobial …

Diagnostics, therapy and outcome prediction in abdominal sepsis: current standards and future perspectives

A Hecker, F Uhle, T Schwandner, W Padberg… - … archives of surgery, 2014 - Springer
Purpose In the perioperative phase, sepsis and sepsis-associated death are the most
important problems for both the surgeon and the intensivist. Critically ill patients profit from …

Chronic critical illness in patients with sepsis is associated with persistent anemia, inflammation, and impaired functional outcomes

ED Carmichael, CG Apple, KB Kannan… - The American …, 2023 - journals.sagepub.com
Introduction Survivors of sepsis will progress towards rapid recovery (RAP) or enter a state
of persistent organ dysfunction and chronic critical illness (CCI). Independently, anemia is …

Determinants of Inadequate Empiric Antimicrobial Therapy in ICU Sepsis Patients in Al-Madinah Al-Munawwarah, Saudi Arabia: A Comparison of Artificial Neural …

AHH Dala Ali, SN Harun, N Othman, B Ibrahim… - Antibiotics, 2023 - mdpi.com
In the management of sepsis, providing adequate empiric antimicrobial therapy is one of the
most important pillars of sepsis management. Therefore, it is important to evaluate the …

[HTML][HTML] Evaluation of antibiotic use among sepsis patients in an intensive care unit: a cross-sectional study at a referral hospital in Indonesia

RS Dewi, M Radji, R Andalusia - Sultan Qaboos University medical …, 2018 - ncbi.nlm.nih.gov
Objectives This study aimed to evaluate the appropriateness of antibiotic use and factors
associated with outcomes among sepsis patients in an intensive care unit (ICU). Methods …

Compliance with an empirical antimicrobial protocol improves the outcome of complicated intra-abdominal infections: a prospective observational study

M Guilbart, E Zogheib, A Ntouba… - BJA: British Journal …, 2016 - academic.oup.com
Background Despite improvements in medical and surgical care, mortality attributed to
complicated intra-abdominal infections (cIAI) remains high. Appropriate initial antimicrobial …