Epidemiology of sepsis in surgical patients
Despite advances in surgical critical care, sepsis among surgical patients continues to be a
common and serious problem. As the population ages, the incidence of sepsis in the United …
common and serious problem. As the population ages, the incidence of sepsis in the United …
Early diagnosis and evidence-based care of surgical sepsis
Sepsis continues to be a common and serious problem among surgical patients. It is a
leading cause of both morbidity and mortality in the perioperative period. The early …
leading cause of both morbidity and mortality in the perioperative period. The early …
Evidence for persistent immune suppression in patients who develop chronic critical illness after sepsis
JA Stortz, TJ Murphy, SL Raymond, JC Mira, R Ungaro… - Shock, 2018 - journals.lww.com
Background: Many sepsis survivors develop chronic critical illness (CCI) and are assumed
to be immunosuppressed, but there is limited clinical evidence to support this. We sought to …
to be immunosuppressed, but there is limited clinical evidence to support this. We sought to …
Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis
MKK Hollen, JA Stortz, D Darden, ML Dirain… - Critical Care, 2019 - Springer
Background Sepsis is an increasingly significant challenge throughout the world as one of
the major causes of patient morbidity and mortality. Central to the host immunologic …
the major causes of patient morbidity and mortality. Central to the host immunologic …
Machine learning techniques to identify antimicrobial resistance in the intensive care unit
S Martínez-Agüero, I Mora-Jiménez, J Lérida-García… - Entropy, 2019 - mdpi.com
The presence of bacteria with resistance to specific antibiotics is one of the greatest threats
to the global health system. According to the World Health Organization, antimicrobial …
to the global health system. According to the World Health Organization, antimicrobial …
Diagnostics, therapy and outcome prediction in abdominal sepsis: current standards and future perspectives
A Hecker, F Uhle, T Schwandner, W Padberg… - … archives of surgery, 2014 - Springer
Purpose In the perioperative phase, sepsis and sepsis-associated death are the most
important problems for both the surgeon and the intensivist. Critically ill patients profit from …
important problems for both the surgeon and the intensivist. Critically ill patients profit from …
Chronic critical illness in patients with sepsis is associated with persistent anemia, inflammation, and impaired functional outcomes
ED Carmichael, CG Apple, KB Kannan… - The American …, 2023 - journals.sagepub.com
Introduction Survivors of sepsis will progress towards rapid recovery (RAP) or enter a state
of persistent organ dysfunction and chronic critical illness (CCI). Independently, anemia is …
of persistent organ dysfunction and chronic critical illness (CCI). Independently, anemia is …
Determinants of Inadequate Empiric Antimicrobial Therapy in ICU Sepsis Patients in Al-Madinah Al-Munawwarah, Saudi Arabia: A Comparison of Artificial Neural …
In the management of sepsis, providing adequate empiric antimicrobial therapy is one of the
most important pillars of sepsis management. Therefore, it is important to evaluate the …
most important pillars of sepsis management. Therefore, it is important to evaluate the …
[HTML][HTML] Evaluation of antibiotic use among sepsis patients in an intensive care unit: a cross-sectional study at a referral hospital in Indonesia
Objectives This study aimed to evaluate the appropriateness of antibiotic use and factors
associated with outcomes among sepsis patients in an intensive care unit (ICU). Methods …
associated with outcomes among sepsis patients in an intensive care unit (ICU). Methods …
Compliance with an empirical antimicrobial protocol improves the outcome of complicated intra-abdominal infections: a prospective observational study
M Guilbart, E Zogheib, A Ntouba… - BJA: British Journal …, 2016 - academic.oup.com
Background Despite improvements in medical and surgical care, mortality attributed to
complicated intra-abdominal infections (cIAI) remains high. Appropriate initial antimicrobial …
complicated intra-abdominal infections (cIAI) remains high. Appropriate initial antimicrobial …