Endocrine disruptor compounds—a cause of impaired immune tolerance driving inflammatory disorders of pregnancy?

JE Schjenken, ES Green, TS Overduin… - Frontiers in …, 2021 - frontiersin.org
Endocrine disrupting compounds (EDCs) are prevalent and ubiquitous in our environment
and have substantial potential to compromise human and animal health. Amongst the …

Data-driven modeling of pregnancy-related complications

C Espinosa, M Becker, I Marić, RJ Wong… - Trends in molecular …, 2021 - cell.com
A healthy pregnancy depends on complex interrelated biological adaptations involving
placentation, maternal immune responses, and hormonal homeostasis. Recent advances in …

Re‐evaluation of the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs

EFSA Panel on Food Contact Materials … - EFSA …, 2023 - Wiley Online Library
In 2015, EFSA established a temporary tolerable daily intake (t‐TDI) for BPA of 4 μg/kg body
weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the …

[HTML][HTML] Periodic changes in the N-Glycosylation of Immunoglobulin G during the Menstrual cycle

J Jurić, H Peng, M Song, F Vučković, J Šimunović… - Engineering, 2023 - Elsevier
Immunoglobulin G (IgG) is the most abundant plasma glycoprotein and a prominent humoral
immune mediator. Glycan composition affects the affinity of IgG to ligands and consequent …

[HTML][HTML] Hormones in malaria infection: influence on disease severity, host physiology, and therapeutic opportunities

A Das, M Suar, KS Reddy - Bioscience Reports, 2024 - pmc.ncbi.nlm.nih.gov
Human malaria, caused by Plasmodium parasites, is a fatal disease that disrupts the host's
physiological balance and affects the neuroendocrine system. This review explores how …

Obstetric risk in pregnancy interacts with hair cortisone levels to reduce gestational length

J Musana, CR Cohen, M Kuppermann… - Frontiers in Global …, 2022 - frontiersin.org
Background Maternal psychological stress has been linked to preterm birth. However, the
differential contribution of psychological stress versus stress hormones is not clear. Studies …

Cannabidiol mitigates Lipopolysaccharide-Induced Pancreatic Pathology: a promising therapeutic strategy

S Topsakal, O Ozmen, NF Karakuyu… - Cannabis and …, 2024 - liebertpub.com
Background: Lipopolysaccharides (LPSs) are a component of certain types of bacteria and
can induce an inflammatory response in the body, including in the pancreas. Cannabidiol …

[HTML][HTML] Understanding immune system dysfunction and its context in mood disorders: psychoneuroimmunoendocrinology and clinical interventions

MA Ortega, O Fraile-Martinez… - Military Medical …, 2024 - pmc.ncbi.nlm.nih.gov
Mood disorders include a set of psychiatric manifestations of increasing prevalence in our
society, being mainly represented by major depressive disorder (MDD) and bipolar disorder …

[HTML][HTML] The Role of 11-Oxygenated Androgens and Endocrine Disruptors in Androgen Excess Disorders in Women

J Vitku, A Varausova, T Skodova, L Kolatorova… - International Journal of …, 2024 - mdpi.com
Polycystic ovary syndrome (PCOS) and idiopathic hirsutism (IH) are androgen excess
disorders requiring the determination of classic androgen levels for diagnosis. 11 …

[HTML][HTML] Transcriptomics-based analysis of sex-differentiated mechanisms of hepatotoxicity in zebrafish after long-term exposure to bisphenol AF

X Zhao, Y Zhang, T Yu, L Cai, J Liang, Z Chen… - Ecotoxicology and …, 2023 - Elsevier
Bisphenol AF (BPAF) is an emerging endocrine-disrupting chemical (EDC) prevalent in the
environment as one of the main substitutes for bisphenol A. Sex-specific effects of EDCs …