Current perspective on the challenges in the development of metformin orally disintegrating tablets (ODTs)

MF bin Roslan, RT Widodo - Journal of Drug Delivery Science and …, 2023 - Elsevier
Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by persistent
hyperglycaemia with significant morbidity and mortality rates. Currently, metformin is a drug …

Design and optimization of silymarin loaded in lyophilized fast melt tablets to attenuate lung toxicity induced via HgCl2 in rats

NM Sheta, SA Boshra, MA Mamdouh… - Drug Delivery, 2022 - Taylor & Francis
The present study aimed to develop fast melting tablets (FMTs) using silymarin (SM) owing
to FMTs rapid disintegration and dissolution. FMTs represent a pathway to help patients to …

Effect of co-processed excipient type on properties of orodispersible tablets containing captopril, tramadol, and domperidone

T Tranová, J Loskot, O Navrátil, W Brniak… - International Journal of …, 2023 - Elsevier
An important feature of orodispersible tablets (ODTs) is the convenient administration of the
drugs, in some cases, faster onset of action, stability maintenance, and dose precision. This …

Computer-aided optimization of carbidopa/levodopa orally disintegrating tablets

F Qin, C Wan, Y Zhang - Drug Development and Industrial …, 2024 - Taylor & Francis
Objective This study aimed to optimize the formulation of carbidopa/levodopa orally
disintegrating tablets (ODTs) in order to improve their disintegration performance, and …

[PDF][PDF] Development and evaluation of taste masked oro-disintegrating tablets of itopride hcl using different co-processed excipients: pharmacokinetics study on rabbits

R Abdelmonem, M Eltahan, M El-Nabarawi - Int J App Pharm, 2022 - researchgate.net
Objective: This study aimed to mask the bitter taste of itopride HCl using the solid dispersion
method by solvent evaporation technique and formulate an oral disintegrating tablet (ODT) …

Formulation and in vitro evaluation of pramipexole orally disintegrating tablets for pediatric restless leg syndrome

Ö Türkmen, L Pozharani, M Amel - Journal of Research in …, 2023 - avesis.yyu.edu.tr
In this study, orally disintegrating tablets (ODT) of pramipexole dihydrochloride monohydrate
(PPX) was developed with direct compression method by using ready-to-use excipients …

[PDF][PDF] Measurement of Process Capability of Manufacturing Process of Levetiracetam by Applying Concept of Six Sigma

C Chandarana, P Rai, D Jadhav - Ind. J. Pharm. Edu. Res, 2023 - ijper.org
Background: A process capacity study is a study that uses capability indices to compare the
output of an in-control process to specification constraints. Cp, Cpk, Ppk, and Pp are some of …