Glioma: molecular signature and crossroads with tumor microenvironment
L Barthel, M Hadamitzky, P Dammann… - Cancer and Metastasis …, 2022 - Springer
In patients with glioblastoma, the average survival time with current treatments is short,
mainly due to recurrences and resistance to therapy. This insufficient treatment success is, in …
mainly due to recurrences and resistance to therapy. This insufficient treatment success is, in …
[HTML][HTML] MicroRNA-based therapy for glioblastoma: Opportunities and challenges
Q Lei, Y Yang, W Zhou, W Liu, Y Li, N Qi, Q Li… - European Journal of …, 2023 - Elsevier
Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor and
is characterized by high mortality and morbidity rates and unpredictable clinical behavior …
is characterized by high mortality and morbidity rates and unpredictable clinical behavior …
[HTML][HTML] Integrated clustering signature of genomic heterogeneity, stemness and tumor microenvironment predicts glioma prognosis and immunotherapy response
Y Wu, M Mao, LJ Wang - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Background: Glioma is the most frequent primary tumor of the central nervous system. The
high heterogeneity of glioma tumors enables them to adapt to challenging environments …
high heterogeneity of glioma tumors enables them to adapt to challenging environments …
Immunomodulatory effect of microglia-released cytokines in gliomas
M Lanza, G Casili, M Campolo, I Paterniti, C Colarossi… - Brain sciences, 2021 - mdpi.com
Microglia, a type of differentiated tissue macrophage, are considered to be the most plastic
cell population of the central nervous system (CNS). Microglia substantially contribute to the …
cell population of the central nervous system (CNS). Microglia substantially contribute to the …
The Spicy Science of Dendrimers in the Realm of Cancer Nanomedicine: A Report from the COST Action CA17140 Nano2Clinic
S Pricl - Pharmaceutics, 2023 - mdpi.com
COST Action CA17140 Cancer Nanomedicine—from the bench to the bedside
(Nano2Clinic,) is the first, pan-European interdisciplinary network of representatives from …
(Nano2Clinic,) is the first, pan-European interdisciplinary network of representatives from …
Enhanced expression of pentraxin-3 in glioblastoma cells correlates with increased invasion and IL8-VEGF signaling axis
UV Wesley, I Sutton, PA Clark, K Cunningham… - Brain research, 2022 - Elsevier
Glioblastoma (GB) is highly invasive and resistant to multimodal treatment partly due to
distorted vasculature and exacerbated inflammation. The aggressiveness of brain tumors …
distorted vasculature and exacerbated inflammation. The aggressiveness of brain tumors …
Transcriptomic analysis unveils bona fide molecular signatures of microglia under conditions of homeostasis and viral encephalitis
F Mulenge, OL Gern, LM Busker, A Aringo… - Journal of …, 2024 - Springer
Microglia serve as a front-line defense against neuroinvasive viral infection, however,
determination of their actual transcriptional profiles under conditions of health and disease is …
determination of their actual transcriptional profiles under conditions of health and disease is …
M2 macrophages serve as critical executor of innate immunity in chronic allograft rejection
H Zhang, Z Li, W Li - Frontiers in immunology, 2021 - frontiersin.org
Allograft functional failure due to acute or chronic rejection has long been a major concern in
the area of solid organ transplantation for decades. As critical component of innate immune …
the area of solid organ transplantation for decades. As critical component of innate immune …
Endoplasmic Reticulum Stress in the Brain Tumor Immune Microenvironment
Immunotherapy has emerged as a powerful strategy for halting cancer progression.
However, primary malignancies affecting the brain have been exempt to this success …
However, primary malignancies affecting the brain have been exempt to this success …
Mapping the tumor-infiltrating immune cells during glioblastoma progression
S Lakshmanachetty, SS Mitra - Nature immunology, 2022 - nature.com
Mapping the tumor-infiltrating immune cells during glioblastoma progression | Nature
Immunology Skip to main content Thank you for visiting nature.com. You are using a …
Immunology Skip to main content Thank you for visiting nature.com. You are using a …