[HTML][HTML] An artificial protein modulator reprogramming neuronal protein functions

P Lin, B Zhang, H Yang, S Yang, P Xue, Y Chen… - Nature …, 2024 - nature.com
Reversible protein phosphorylation, regulated by protein phosphatases, fine-tunes target
protein function and plays a vital role in biological processes. Dysregulation of this process …

The inhibitory mechanism of aurintricarboxylic acid targeting serine/threonine phosphatase Stp1 in Staphylococcus aureus: insights from molecular dynamics …

T Liu, T Yang, M Gao, K Chen, S Yang, K Yu… - Acta Pharmacologica …, 2019 - nature.com
Abstract Serine/threonine phosphatase (Stp1) is a member of the bacterial Mg2+-or Mn2+-
dependent protein phosphatase/protein phosphatase 2C family, which is involved in the …

Structural Insight into the Mechanism of Staphylococcus aureus Stp1 Phosphatase

T Yang, T Liu, J Gan, K Yu, K Chen, W Xue… - ACS Infectious …, 2019 - ACS Publications
Staphylococcus aureus Stp1, which belongs to the bacterial metal-dependent protein
phosphatase (PPM) family, is a promising candidate for antivirulence targeting. How Stp1 …

[HTML][HTML] Crystal Structures of Pyrophosphatase from Acinetobacter baumannii: Snapshots of Pyrophosphate Binding and Identification of a Phosphorylated Enzyme …

Y Si, X Wang, G Yang, T Yang, Y Li, GJ Ayala… - International Journal of …, 2019 - mdpi.com
All living things have pyrophosphatases that hydrolyze pyrophosphate and release energy.
This energetically favorable reaction drives many energetically unfavorable reactions. An …

[图书][B] Characterization and Study of the Physiological Role of CTL0511, a Chlamydial Protein Phosphatase Type 2C

JE Claywell - 2019 - search.proquest.com
Chlamydia are obligate intracellular bacterial pathogens that are responsible for infectious
blindness, sexually transmitted infections, and acute respiratory disease in humans. These …