[HTML][HTML] High-density lipoproteins during sepsis: from bench to bedside

S Tanaka, D Couret, A Tran-Dinh, J Duranteau… - Critical Care, 2020 - Springer
High-density lipoproteins (HDLs) represent a family of particle characterized by the
presence of apolipoprotein AI (apoA-I) and by their ability to transport cholesterol from …

Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

MJ Chapman, HN Ginsberg, P Amarenco… - European heart …, 2011 - academic.oup.com
Even at low-density lipoprotein cholesterol (LDL-C) goal, patients with cardiometabolic
abnormalities remain at high risk of cardiovascular events. This paper aims (i) to critically …

Prevalence of and risk factors for diabetic peripheral neuropathy in youth with type 1 and type 2 diabetes: SEARCH for diabetes in youth study

M Jaiswal, J Divers, D Dabelea, S Isom, RA Bell… - Diabetes …, 2017 - Am Diabetes Assoc
OBJECTIVE We assessed the prevalence of and risk factors for diabetic peripheral
neuropathy (DPN) in youth with type 1 diabetes (T1D) and type 2 diabetes (T2D) enrolled in …

High-density lipoproteins: nature's multifunctional nanoparticles

R Kuai, D Li, YE Chen, JJ Moon, A Schwendeman - ACS nano, 2016 - ACS Publications
High-density lipoproteins (HDL) are endogenous nanoparticles involved in the transport and
metabolism of cholesterol, phospholipids, and triglycerides. HDL is well-known as the …

HDL-targeted therapies: progress, failures and future

BA Kingwell, MJ Chapman, A Kontush… - Nature reviews Drug …, 2014 - nature.com
Since the discovery in the 1970s that plasma levels of high-density lipoprotein cholesterol
(HDL-C) are inversely associated with cardiovascular outcome, it has been postulated that …

HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms

M Navab, ST Reddy, BJ Van Lenten… - Nature Reviews …, 2011 - nature.com
The lipoprotein HDL has two important roles: first, it promotes reverse cholesterol transport,
and second, it modulates inflammation. Epidemiological studies show that HDL-cholesterol …

[HTML][HTML] ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

AJ Murphy, M Akhtari, S Tolani, T Pagler… - The Journal of …, 2011 - Am Soc Clin Investig
Leukocytosis is associated with increased cardiovascular disease risk in humans and
develops in hypercholesterolemic atherosclerotic animal models. Leukocytosis is associated …

The emerging role of HDL in glucose metabolism

BG Drew, KA Rye, SJ Duffy, P Barter… - Nature Reviews …, 2012 - nature.com
A low plasma level of HDL cholesterol is an atherosclerotic risk factor; however, emerging
evidence suggests that low HDL levels might also contribute to the pathophysiology of type …

HDL function and atherosclerosis: reactive dicarbonyls as promising targets of therapy

MRF Linton, PG Yancey, H Tao, SS Davies - Circulation Research, 2023 - Am Heart Assoc
Epidemiologic studies detected an inverse relationship between HDL (high-density
lipoprotein) cholesterol (HDL-C) levels and atherosclerotic cardiovascular disease …

Anti-inflammatory effects of HDL (high-density lipoprotein) in macrophages predominate over proinflammatory effects in atherosclerotic plaques

P Fotakis, V Kothari, DG Thomas… - … , and vascular biology, 2019 - Am Heart Assoc
Objective: HDL (high-density lipoprotein) infusion reduces atherosclerosis in animal models
and is being evaluated as a treatment in humans. Studies have shown either anti-or …