[HTML][HTML] Microsomal glutathione transferase 1 in cancer and the regulation of ferroptosis
J Zhang, Z Ye, R Morgenstern… - Advances in cancer …, 2023 - ncbi.nlm.nih.gov
Abstract Microsomal glutathione transferase 1 (MGST1) is a member of the MAPEG family
(membrane associated proteins in eicosanoid and glutathione metabolism), defined …
(membrane associated proteins in eicosanoid and glutathione metabolism), defined …
Extracellular vesicles in virus infection and pathogenesis
RP McNamara, DP Dittmer - Current opinion in virology, 2020 - Elsevier
Highlights•Distinct viruses converged to usurp extracellular vesicle signaling.•Extracellular
vesicles transfer virus-encoded factors during latency.•Extracellular vesicles can be used for …
vesicles transfer virus-encoded factors during latency.•Extracellular vesicles can be used for …
Time-resolved transcriptomes reveal diverse B cell fate trajectories in the early response to Epstein-Barr virus infection
Epstein-Barr virus infection of B lymphocytes elicits diverse host responses via well-adapted
transcriptional control dynamics. Consequently, this host-pathogen interaction provides a …
transcriptional control dynamics. Consequently, this host-pathogen interaction provides a …
Oncogenic viruses as entropic drivers of cancer evolution
I Tempera, PM Lieberman - Frontiers in virology, 2021 - frontiersin.org
Viral infection is an indisputable causal factor for nearly 17% of all human cancers.
However, the diversity and complexity of oncogenic mechanisms raises new questions as to …
However, the diversity and complexity of oncogenic mechanisms raises new questions as to …
Single-cell RNA-seq reveals transcriptomic heterogeneity mediated by host–pathogen dynamics in lymphoblastoid cell lines
ED SoRelle, J Dai, EN Bonglack, EM Heckenberg… - Elife, 2021 - elifesciences.org
Lymphoblastoid cell lines (LCLs) are generated by transforming primary B cells with Epstein–
Barr virus (EBV) and are used extensively as model systems in viral oncology, immunology …
Barr virus (EBV) and are used extensively as model systems in viral oncology, immunology …
Monocarboxylate transporter antagonism reveals metabolic vulnerabilities of viral-driven lymphomas
EN Bonglack, JE Messinger… - Proceedings of the …, 2021 - National Acad Sciences
Epstein–Barr virus (EBV) is a ubiquitous herpesvirus that typically causes asymptomatic
infection but can promote B lymphoid tumors in the immune suppressed. In vitro, EBV …
infection but can promote B lymphoid tumors in the immune suppressed. In vitro, EBV …
Epstein-Barr virus perpetuates B cell germinal center dynamics and generation of autoimmune-associated phenotypes in vitro
Human B cells encompass functionally diverse lineages and phenotypic states that
contribute to protective as well as pathogenic responses. Epstein-Barr virus (EBV) provides …
contribute to protective as well as pathogenic responses. Epstein-Barr virus (EBV) provides …
MicroRNA-mediated control of Epstein–Barr virus infection and potential diagnostic and therapeutic implications
RL Skalsky - Current Opinion in Virology, 2022 - Elsevier
Highlights•MicroRNAs (miRNAs) are often dysregulated in Epstein–Barr virus (EBV)
infection and cancers.•EBV usurps miRNAs to evade immune recognition and reprogram the …
infection and cancers.•EBV usurps miRNAs to evade immune recognition and reprogram the …
Comprehensive Epstein-Barr virus transcriptome by RNA-sequencing in angioimmunoblastic T cell lymphoma (AITL) and other lymphomas
N Bayda, V Tilloy, A Chaunavel, R Bahri, MA Halabi… - Cancers, 2021 - mdpi.com
Simple Summary Angioimmunoblastic T cell lymphoma (AITL) is probably the most common
peripheral T-cell lymphoma. This pathology, although rare, is more common in Europe than …
peripheral T-cell lymphoma. This pathology, although rare, is more common in Europe than …
Viral and host factors drive a type 1 Epstein–Barr virus spontaneous lytic phenotype
KA Willard, AP Barry, CI Oduor, JM Ong'echa, JA Bailey… - Mbio, 2023 - Am Soc Microbiol
Epstein–Barr virus (EBV) is a cancer and autoimmune disease-associated gamma-
herpesvirus that infects the majority of adults worldwide. After initial infection, EBV generally …
herpesvirus that infects the majority of adults worldwide. After initial infection, EBV generally …