Estrogen receptors (ERs) regulate multiple complex physiological processes in humans.
Abnormal ER signaling may result in various disorders, including reproductive system …

The primary female sex hormones, estrogens, are responsible for the control of functions of
the female reproductive system, as well as the development of secondary sexual …

Oestrogens and their receptors contribute broadly to physiology and diseases. In
premenopausal women, endogenous oestrogens protect against cardiovascular, metabolic …

The actions of estrogens and related estrogenic molecules are complex and multifaceted in
both sexes. A wide array of natural, synthetic, and therapeutic molecules target pathways …

Although hormones such as glucocorticoids have been broadly accepted in recent decades
as general neuromodulators of memory processes, sex steroid hormones such as the potent …

Estrogens have historically been associated with female reproduction, but work over the last
two decades established that estrogens and their main nuclear receptors (ESR1 and ESR2) …

Endometrial cancer is the most common gynecological cancer in the developed world, and it
is one of the few cancer types that is becoming more prevalent and leading to more deaths …

Estrogens are the primary female sex hormones and play important roles in both
reproductive and non-reproductive systems. Estrogens can be synthesized in non …

The peri-menopause or menopausal transition—the time period that surrounds the final
years of a woman's reproductive life—is associated with profound reproductive and …

Inflammatory activation of microglia is a hallmark of several disorders of the central nervous
system. In addition to protecting the brain against inflammatory insults, microglia are …