The 18 glycosyl hydrolase family of chitinases is an ancient gene family that is widely
expressed from prokaryotes to eukaryotes. In mammals, despite the absence of endogenous …

Therapeutic peptides/proteins and protein-based antigens are chemically and structurally
labile compounds, which are almost exclusively administered by parenteral injections …

Due to the fact that some individuals are allergic to crustaceans, the presumed relationship
between allergy and the presence of chitin in crustaceans has been investigated. In vivo …

Chitin, the second most abundant polysaccharide in nature, is commonly found in lower
organisms such as fungi, crustaceans, and insects, but not in mammals. Although the non …

Since the early 1990s polymer–protein conjugates (included PEGylated enzymes and
cytokines), polymeric drugs and polymeric sequestrants have been entering the market as …

Chitooligosaccharides (CHOS) are oligomers of β-(1–4) linked N-acetylglucosamine and D-
glucosamine that are produced from chitin or chitosan using different enzymatic or chemical …

Atopic asthma is a chronic inflammatory pulmonary disease characterised by recurrent
episodes of wheezy, laboured breathing with an underlying Th2 cell-mediated inflammatory …

It is known that down-regulation of the immune response may be associated with the
progenesis, development and prognosis of cancer or infectious diseases. Up-regulating the …

A major obstacle in the development of polymeric nanoparticles (NPs) as effective drug
delivery vesicles is the rapid clearance from blood. In order to realize a significant …

A natural long-chain polymer, chitin is the main component of the cell walls of fungi, the
exoskeletons of arthropods (including crustaceans and insects), the radulas of mollusks, and …