Phage penetration of eukaryotic cells: practical implications

M Żaczek, A Górski, A Skaradzińska… - Future …, 2019 - Taylor & Francis
The inability to infect eukaryotic cells has been considered as the most undeniable feature of
all bacterial viruses. Such specificity, limited only for bacterial hosts, raises questions about …

Phage Display as a Medium for Target Therapy Based Drug Discovery, Review and Update

S Jahandar-Lashaki, S Farajnia… - Molecular …, 2024 - Springer
Phage libraries are now amongst the most prominent approaches for the identification of
high-affinity antibodies/peptides from billions of displayed phages in a specific library …

Lytic bacteriophages induce the secretion of antiviral and proinflammatory cytokines from human respiratory epithelial cells

PF Zamora, TG Reidy, CR Armbruster, M Sun… - Plos …, 2024 - journals.plos.org
Phage therapy is a therapeutic approach to treat multidrug-resistant (MDR) infections that
employs lytic bacteriophages (phages) to eliminate bacteria. Despite the abundant evidence …

Development of a new affinity maturation protocol for the construction of an internalizing anti-nucleolin antibody library

R Ribeiro, JN Moreira, J Goncalves - Scientific Reports, 2024 - nature.com
Over the last decades, monoclonal antibodies have substantially improved the treatment of
several conditions. The continuous search for novel therapeutic targets and improvements in …

Application of phage display technology for the production of antibodies against Streptococcus suis serotype 2

P Sulong, N Anudit, S Nuanualsuwan, S Mariela… - PLoS …, 2021 - journals.plos.org
Streptococcus suis (S. suis) serotype 2 infection is a problem in the swine industry and
responsible for most cases of human infection worldwide. Since current multiplex PCR …

Improved gene transfer with functionalized hollow mesoporous silica nanoparticles of reduced cytotoxicity

Z Zhan, X Zhang, J Huang, Y Huang, Z Huang, X Pan… - Materials, 2017 - mdpi.com
Gene therapy is a promising strategy for treatment of genetically caused diseases.
Successful gene delivery requires an efficient carrier to transfer the desired gene into host …

One-pot, degradable, silica nanocarriers with encapsulated oligonucleotides for mitochondrial specific targeting

C Trayford, A Wilhalm, P Habibovic, H Smeets… - Discover Nano, 2023 - Springer
Mutations in nuclear and mitochondrial genes are responsible for severe chronic disorders
such as mitochondrial myopathies. Gene therapy using antisense oligonucleotides is a …

[HTML][HTML] Lytic bacteriophages interact with respiratory epithelial cells and induce the secretion of antiviral and proinflammatory cytokines

PF Zamora, TG Reidy, CR Armbruster, M Sun… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Phage therapy is a therapeutic approach to treat multidrug resistant infections that employs
lytic bacteriophages (phages) to eliminate bacteria. Despite the abundant evidence for its …

One-pot, degradable, silica nanocarriers with encapsulated oligonucleotides for mitochondrial specific delivery

C Trayford, A Wilhalm, P Habibovic, H Smeets… - 2023 - researchsquare.com
Mutations in nuclear and mitochondrial genes are responsible for severe chronic disorders
such as mitochondrial myopathies (MM). Gene therapy using antisense oligonucleotides is a …

High activity chimeric snake gamma-type phospholipase A2 inhibitor created by DNA shuffling

S Sun, D Zhang, J Zhang, C Huang, Y Xiong - Toxicon, 2018 - Elsevier
The gamma-type inhibitor of snake venom phospholipase A 2 (PLIγ) is expressed
extensively in livers of both venomous and non-venomous snakes. It is not clear why PLIγs …