Although antiretroviral therapy has transformed human immunodeficiency virus-type 1 (HIV-
1) from a deadly infection into a chronic disease, it does not clear the viral reservoir, leaving …

Highlights•Persistent oncogenic Epstein Barr virus (EBV) infection is kept in check by
cytotoxic lymphocytes.•Primary immunodeficiencies suggest these to primarily be CD27+ …

Primary immunodeficiencies in the costimulatory molecule CD27 and its ligand, CD70,
predispose for pathologies of uncontrolled Epstein-Barr virus (EBV) infection in nearly all …

Herpesvirus infections shape the human natural killer (NK) cell compartment. While Epstein-
Barr virus (EBV) expands immature NKG2A+ NK cells, human cytomegalovirus (CMV) drives …

The Epstein Barr virus (EBV) is one of the prominent human tumor viruses, and it is
efficiently immune-controlled in most virus carriers. Cytotoxic lymphocytes strongly expand …

In most individuals, EBV maintains a life-long asymptomatic latent infection. However, EBV
can induce the formation of B cell lymphomas in immune suppressed individuals including …

Background: The aim of the present study was to evaluate the immunological profile of adult
HIV-1+ patients coinfected with primary Epstein–Barr virus (EBV) infection who were free of …

Epstein–Barr virus (EBV) is an oncovirus ubiquitously distributed and associated with
different types of cancer. The reason why only a group of infected people develop cancer is …

Since Epstein–Barr Virus (EBV) was isolated 60 years ago, it has been studied clinically,
epidemiologically, immunologically, and molecularly in the ensuing years. These combined …

Epstein Barr virus (EBV) is one of the most successful pathogens of humans, persistently
colonizing more than 95% of the adult human population. At the same time EBV encodes …