Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …

Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

The CRISPR-Cas9 RNA-guided DNA endonuclease has contributed to an explosion of
advances in the life sciences that have grown from the ability to edit genomes within living …

With rapid advances in understanding molecular pathogenesis of human diseases in the era
of genome sciences and systems biology, it is anticipated that increasing numbers of …

Structural, biochemical and biophysical studies of eukaryotic membrane proteins are often
hampered by difficulties in overexpression of the candidate molecule. Baculovirus …

Gene therapy is the process of introducing foreign genomic materials into host cells to elicit
a therapeutic benefit. Although initially the main focus of gene therapy was on special …

Lentiviral vectors (LVs) have emerged as potent and versatile vectors for ex vivo or in vivo
gene transfer into dividing and nondividing cells. Robust phenotypic correction of diseases …

ABSTRACT SARS-CoV-2, a betacoronavirus, is the cause of the COVID-19 pandemic. The
SARS-CoV-2 spike (S) glycoprotein trimer mediates virus entry into host cells and cytopathic …

MicroRNAs (miRs) regulate gene expression at the posttranscriptional level and play crucial
roles in vascular integrity. As such, they may have a role in modifying abdominal aortic …

This review provides comprehensive information about the advances in gene therapy in the
anterior segment of the eye, including cornea, conjunctiva, lacrimal gland, and trabecular …