High density lipoproteins and arteriosclerosis: role of cholesterol efflux and reverse cholesterol transport

A Von Eckardstein, JR Nofer… - … , thrombosis, and vascular …, 2001 - Am Heart Assoc
High density lipoprotein (HDL) cholesterol is an important risk factor for coronary heart
disease, and HDL exerts various potentially antiatherogenic properties, including the …

HDL and atherosclerotic cardiovascular disease: genetic insights into complex biology

RS Rosenson, HB Brewer Jr, PJ Barter… - Nature Reviews …, 2018 - nature.com
Plasma levels of HDL cholesterol (HDL-C) predict the risk of cardiovascular disease at the
epidemiological level, but a direct causal role for HDL in cardiovascular disease remains …

[HTML][HTML] Antioxidant and anti-inflammatory role of paraoxonase 1: implication in arteriosclerosis diseases

D Litvinov, H Mahini, M Garelnabi - North American journal of …, 2012 - ncbi.nlm.nih.gov
Abstract Paraoxonase 1 (PON1) is a hydrolytic enzyme with wide range of substrates, and
capability to protect against lipid oxidation. Despite of the large number of compounds that …

APOA2, dietary fat, and body mass index: replication of a gene-diet interaction in 3 independent populations

D Corella, G Peloso, DK Arnett… - Archives of internal …, 2009 - jamanetwork.com
Background Nutrigenetics studies the role of genetic variation on interactions between diet
and health, aiming to provide more personalized dietary advice. However, replication has …

Anti‐oxidant properties of high‐density lipoprotein and atherosclerosis

EA Podrez - Clinical and Experimental Pharmacology and …, 2010 - Wiley Online Library
High‐density lipoprotein (HDL) is one of the major carriers of cholesterol in the blood. It
attracts particular attention because, in contrast with other lipoproteins, many physiological …

Apolipoprotein A-II, HDL metabolism and atherosclerosis

A Tailleux, P Duriez, JC Fruchart, V Clavey - Atherosclerosis, 2002 - Elsevier
Apolipoprotein (Apo) AI and apo A-II are the major apolipoproteins of HDL. It is clearly
demonstrated that there are inverse relationships between HDL–cholesterol and apo AI …

[HTML][HTML] Role of apoA-II in lipid metabolism and atherosclerosis: advances in the study of an enigmatic protein

F Blanco-Vaca, JC Escolà-Gil, JM Martín-Campos… - Journal of lipid …, 2001 - ASBMB
Our understanding of apolipoprotein A-II (apoA-II) physiology is much more limited than that
of apoA-I. However, important and rather surprising advances have been produced, mainly …

Human apolipoprotein A-II enrichment displaces paraoxonase from HDL and impairs its antioxidant properties: a new mechanism linking HDL protein composition …

V Ribas, JL Sánchez-Quesada, R Antón… - Circulation …, 2004 - Am Heart Assoc
Apolipoprotein A-II (apoA-II), the second major high-density lipoprotein (HDL)
apolipoprotein, has been linked to familial combined hyperlipidemia. Human apoA-II …

[HTML][HTML] Anti-inflammatory and cholesterol-reducing properties of apolipoprotein mimetics: a review

CR White, DW Garber, GM Anantharamaiah - Journal of lipid research, 2014 - ASBMB
Reduced levels of HDL cholesterol (HDL-C) are a strong independent predictor of coronary
artery disease (CAD) risk. The major anti-atherogenic function of HDL is to mediate reverse …

The− 256T> C polymorphism in the apolipoprotein A-II gene promoter is associated with body mass index and food intake in the genetics of lipid lowering drugs and …

D Corella, DK Arnett, MY Tsai, EK Kabagambe… - Clinical …, 2007 - academic.oup.com
Abstract Background: Apolipoprotein A-II (APOA2) plays an ambiguous role in lipid
metabolism, obesity, and atherosclerosis. Methods: We studied the association between a …